Spinning-Based High-Intensity Interval Training Induces Greater Cardiopulmonary Adaptations Than Continuous Training in Sedentary College Men

December 29, 2025 updated by: Fooyin University
In recent years, fitness concepts have continuously evolved, with many seeking to improve and enhance their physical condition through exercise to achieve better athletic performance. Aerobic exercise not only increases lipid utilization but also boosts athletic performance. Consequently, various aerobic exercise equipment has become increasingly popular in the market. Due to the pandemic's impact in recent years, people have rarely ventured outdoors, making indoor exercise equipment increasingly popular for home workouts. Spinning has emerged as a widely adopted new fitness activity, accessible to all genders and ages. Many gyms even offer specialized spinning classes with variations in speed and resistance. However, past literature has predominantly focused on continuous-intensity spinning interventions, which do not reflect the diverse training variations found in actual spinning classes. Therefore, this study aims to investigate the effects of incorporating high-intensity interval training (HIIT) into spinning on cardiorespiratory fitness.

Study Overview

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Daliao
      • Kaohsiung City, Daliao, Taiwan, 831301
        • No. 151, Jinxue Rd.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • no regular exercise training in the past six months
  • ability to safely perform high-intensity cycling exercise

Exclusion Criteria:

  • musculoskeletal limitations that prevented cycling exercise
  • recent infection
  • known cardiopulmonary disease or medical history affecting cardiovascular or respiratory function
  • smoking
  • use of medications that may influence cardiopulmonary responses to exercise
  • other contraindications to exercise testing according to the American College of Sports Medicine (ACSM) guidelines

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: high-intense interval training
Performed repeated high-intensity bouts at 75-80% of VO₂ reserve, interspersed with active recovery at 60-65% of VO₂ reserve, using a spinning bike.
performed repeated high-intensity bouts at 75-80% of VO₂ reserve, interspersed with active recovery at 60-65% of VO₂ reserve, using a spinning bike
Placebo Comparator: moderate-intensity continuous training
At approximately 70% of VO₂ reserve, using a spinning bike.
continuously at approximately 70% of VO₂ reserve, using spinning bike
did not perform any exercise training
No Intervention: control group
did not perform any exercise training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
VO2max (ml/kg/mL)
Before intervention and the end of intervention at 6 weeks
Baseline anthropometric of the participants
Time Frame: Before intervention and the end of intervention at 6 weeks
Age (yr)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
VEmax (L/min)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
maximal workload (W)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
AT% (%VO₂max)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
Resting O₂ pulse (mL·beat-¹)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
Max O₂ pulse (mL·beat-¹)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
MIP (cmH2O)
Before intervention and the end of intervention at 6 weeks
Cardiopulmonary fitness
Time Frame: Before intervention and the end of intervention at 6 weeks
MEP (cmH2O)
Before intervention and the end of intervention at 6 weeks
Baseline anthropometric of the participants
Time Frame: Before intervention and the end of intervention at 6 weeks
Height (cm)
Before intervention and the end of intervention at 6 weeks
Baseline anthropometric of the participants
Time Frame: Before intervention and the end of intervention at 6 weeks
Weight (kg)
Before intervention and the end of intervention at 6 weeks
Baseline anthropometric of the participants
Time Frame: Before intervention and the end of intervention at 6 weeks
BMI (kg/m²)
Before intervention and the end of intervention at 6 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
FEV1 (L)
Before intervention and the end of intervention at 6 weeks
Lung functionWeight
Time Frame: Before intervention and the end of intervention at 6 weeks
FVC (L)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
FEV₁/FVC (%)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
FEF25-75% (L·s-¹)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
PEF (L·min-¹)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
MVV (L·min-¹)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
Breathing reserve (%)
Before intervention and the end of intervention at 6 weeks
Lung function
Time Frame: Before intervention and the end of intervention at 6 weeks
Dynamic Index (DI%)
Before intervention and the end of intervention at 6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2024

Primary Completion (Actual)

January 30, 2025

Study Completion (Actual)

February 28, 2025

Study Registration Dates

First Submitted

November 21, 2025

First Submitted That Met QC Criteria

December 29, 2025

First Posted (Actual)

December 30, 2025

Study Record Updates

Last Update Posted (Actual)

December 30, 2025

Last Update Submitted That Met QC Criteria

December 29, 2025

Last Verified

August 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • 113-233

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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