Cross-Cultural Adaptation, Validity, and Reliability of the Wexner Questionnaire in Patients With Constipation

September 21, 2026 updated by: Esra BAYRAMOĞLU DEMİRDÖĞEN, Ahi Evran University Education and Research Hospital

Cross-Cultural Adaptation, Validity, and Reliability of the Wexner Questionnaire

The investigators will conduct a validity and reliability study of the Wexner Constipation Questionnaire, used for constipation, in Turkish. For this purpose, investigators will administer the Wexner Questionnaire, translated from English to Turkish, and the accompanying Constipation Quality of Life Scale to 200 participants. Investigators will repeat the Wexner questionnaire for some participants after two weeks.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

To assess the cultural adaptation, validity, and reliability of the eight-question Wexner Constipation Questionnaire, the questionnaire was first translated from English to Turkish, then back from Turkish to English, and finally back from English to Turkish. The questionnaire was finalized with the collaboration of an internal medicine specialist and a gastroenterologist to prepare the Turkish version. It will then be administered to a minimum of 200 participants, along with the Constipation Quality of Life Questionnaire, previously validated and reliable in Turkish and used for constipation. For reliability, the questionnaire will be repeated for a portion of the participants after two weeks.

Study Type

Observational

Enrollment (Actual)

202

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Centre
      • Kırşehir, Centre, Turkey (Türkiye), 40000
        • Kirşehir Ahi Evran University Physical Therapy and Rehabilitation Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 90 years (Adult, Older Adult)

Accepts Healthy Volunteers

N/A

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Men and women with chronic constipation

Description

Inclusion Criteria:

  1. Being over 18 years of age
  2. Being diagnosed with functional constipation according to Rome IV criteria
  3. Having undergone an anorectal examination by a gastroenterologist
  4. Having no history of neurodegenerative disease (e.g., multiple sclerosis, spinal cord injury, or stroke)
  5. Having no history of metabolic disorders (e.g., diabetes, hypothyroidism, or hypercalcemia)
  6. Having no history of opioid-induced constipation
  7. Having no history of irritable bowel syndrome
  8. Having no history of congenital anorectal abnormality
  9. Having no history of colon cancer or pregnancy
  10. Having the ability to read and write Turkish.

Exclusion Criteria:

  1. Not wanting to continue the study.
  2. Having any complaints, such as anorectal bleeding, during the test-retest interval.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: CASE_ONLY
  • Time Perspectives: PROSPECTIVE

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Application of survey to participants
Time Frame: Baseline (Day 1)

First administration of the Wexner questionnaire to all participants
Baseline (Day 1)
Application of survey to participants
Time Frame: Baseline (Day 1)

First administration of the quality of life questionnaire to all participants
Baseline (Day 1)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Application of survey to participants
Time Frame: Baseline (Day 1)

Wexner questionnaire were administered to the participants a second time two weeks later.
Baseline (Day 1)
Application of survey to participants
Time Frame: Baseline (Day 1)

Quality of life questionnaire were administered to the participants a second time two weeks later.
Baseline (Day 1)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ahi Evran University Education and Research Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 1, 2025

Primary Completion (Actual)

December 12, 2025

Study Completion (Actual)

March 13, 2026

Study Registration Dates

First Submitted

October 28, 2025

First Submitted That Met QC Criteria

January 5, 2026

First Posted (Actual)

January 14, 2026

Study Record Updates

Last Update Posted (Actual)

September 24, 2026

Last Update Submitted That Met QC Criteria

September 21, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KAEU-EBAYRAMOGLUD-003

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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