The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain

Sleep Banking Pre-Surgery for Improved Chronic Post-Surgical Pain: A Pilot Study

This study will evaluate the impact of sleep banking on joint replacement surgery recovery.

Study Overview

• Status: Not yet recruiting
• Conditions: Joint (Knee or Hip Replacement)
• Intervention / Treatment: Behavioral: Sleep banking

Detailed Description

Sleep is emerging as a target for pain management. The purpose of this study is to determine the feasibility and efficacy of extending sleep (sleep "banking") on self-reported pain outcomes post-surgery. This is a prospective, interventional, between-subjects, randomized study with a control condition. Participants will be patients undergoing knee or hip replacement surgery at Naval Medical Center San Diego. Participants will be randomized to either a sleep banking group, where they attempt to extend nightly sleep in the week leading up to surgery, or to a habitual sleep control group, sleeping in their typical pattern for that same period. Sleep and pain will be monitored daily yn the two weeks pre- and one week post-surgery. After that, they will be sent electronic follow-up sleep and pain questionnaires at 1, 3, 6, 9, and 12 weeks post-surgery. Participants in the sleep banking group will also complete additional questionnaire items on the feasibility and implementation of the sleep banking protocol. Feasibility of sleep banking will be assessed by examination of the sleep between groups during the intervention week, as well as by the analysis of the implementation questions. Efficacy will be assessed by examination of self-reported pain outcomes post-surgery by group. The primary hypothesis is that self-reported pain outcomes will be improved in the sleep banking group as compared to the control group.

• Study Type: Interventional
• Enrollment (Estimated): 22
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Mary McDuffie, MS RN; Phone Number: 3015388785; Email: mary.mcduffie.ctr@usuhs.edu

Study Locations

• United States
  • California
    • San Diego, California, United States, 92134
      • Naval Medical Center San Diego
      • Contact: DVCIPM Clinical Research Nurse Manager; Email: alexandra.kane.ctr@usuhs.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Individuals scheduled for a joint replacement surgery (knee or hip) at Naval Medical Center San Diego
• Aged 18-74 years

Exclusion Criteria:

• Individuals < 18 or >74 years of age at enrollment
• Individuals diagnosed with untreated sleep disorders
• Individuals with scheduled timezone travel or work schedule changes (>/= 3 hour time change) in the two weeks before surgery

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Sleep extension; The sleep extension group will add 2 h of sleep per night the week before surgery	Behavioral: Sleep banking; The sleep extension group will add 2 hour of sleep per night the week before surgery
No Intervention: Habitual sleep; The habitual sleep group maintain their usual hours of sleep per night the week before surgery

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pain Intensity	Defense and Veterans Pain Rating Scale. On a scale of 0-10, with higher scores denoting more pain.	Weeks 1-15
Pain Medication Use	Opioid Use Diary	Weeks 1-15

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Physical Function	Patient-Reported Outcomes Measurement Information System (PROMIS) -29 Adult Profile 2.0 Instrument, Physical Function subscale. Each item is scored on a scale 1-5, with 1=without any difficulty and 5=unable to do. Items will be summed and t-scored (0-100), with higher scores denoting less function.	Weeks 1-15
Sleep Disturbance	Patient-Reported Outcomes Measurement Information System (PROMIS) -29 Adult Profile 2.0 Instrument, Sleep Disturbance subscale. Each item is scored on a scale 1-5, with 1=not at all and 5=very much. Items will be summed and t-scored (0-100), with higher scores denoting more sleep disturbance.	Weeks 1-15

Collaborators and Investigators

• Sponsor: Defense and Veterans Center for Integrative Pain Management

Study record dates

Study Major Dates

• Study Start (Estimated): February 15, 2026
• Primary Completion (Estimated): January 1, 2028
• Study Completion (Estimated): January 1, 2028

Study Registration Dates

• First Submitted: January 26, 2026
• First Submitted That Met QC Criteria: January 26, 2026
• First Posted (Actual): February 3, 2026

Study Record Updates

• Last Update Posted (Actual): February 12, 2026
• Last Update Submitted That Met QC Criteria: February 11, 2026
• Last Verified: January 1, 2026

More Information

Terms related to this study

• Keywords: chronic pain; recovery; sleep extension; sleep banking
• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Chronic Pain
• Other Study ID Numbers: USUHS 2025-158

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No