French Registry of CMR Late Gadolinium Enhancement in Myocarditis (MYOCARDITI-LGE)

January 30, 2026 updated by: Assistance Publique - Hôpitaux de Paris

Retrospective French Registry of Cardiovascular Magnetic Resonance Late Gadolinium Enhancement in Patients With Myocarditis

Acute myocarditis is a major cause of death in young adults and carries substantial morbidity, including a significant risk of progression to dilated cardiomyopathy. Current diagnostic and therapeutic strategies remain poorly defined, making risk stratification crucial to enable personalized treatments and reduce mortality and major cardiovascular events.

Study Overview

Status

Not yet recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

5000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study will include all consecutive patients with AM referred for CMR assessment.

Description

Inclusion Criteria:

  1. Age ≥ 18 years
  2. Ability to provide informed non-opposition
  3. AM diagnosis confirmed using CMR, fulfilling the modified Lake Louise diagnostic criteria

Exclusion Criteria:

1. Patients unable to provide informed non-opposition.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
All-cause mortality
Time Frame: From enrollment to the end of follow up at 10 years
All-cause mortality defined using the French national registry of death (INSEE).
From enrollment to the end of follow up at 10 years

Secondary Outcome Measures

Outcome Measure
Time Frame
All-cause death
Time Frame: From enrollment to the end of follow up at 10 years
From enrollment to the end of follow up at 10 years
Heart transplantation
Time Frame: From enrollment to the end of follow up at 10 years
From enrollment to the end of follow up at 10 years
Ventricular arrhythmia
Time Frame: From enrollment to the end of follow up at 10 years
From enrollment to the end of follow up at 10 years
Hospitalisation for acute heart failure
Time Frame: From enrollment to the end of follow up at 10 years
From enrollment to the end of follow up at 10 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assistance Publique - Hôpitaux de Paris

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

February 10, 2026

Primary Completion (Estimated)

February 10, 2036

Study Completion (Estimated)

February 10, 2036

Study Registration Dates

First Submitted

January 30, 2026

First Submitted That Met QC Criteria

January 30, 2026

First Posted (Actual)

February 6, 2026

Study Record Updates

Last Update Posted (Actual)

February 6, 2026

Last Update Submitted That Met QC Criteria

January 30, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • APHP251399

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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