Effects of Powerlifting-Based Training in Athletes (PLBT-ATH)

The Effects of Powerlifting-Based Training on Hormonal, Metabolic, and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial

This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.

Study Overview

• Status: Completed
• Conditions: Physical Fitness; Metabolic Parameters; Hormonal Response
• Intervention / Treatment: Other: Powerlifting-Based Training; Other: Blood Sampling and Laboratory Analysis; Other: Usual Basketball Training

Detailed Description

This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines.

The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Center
    • Tunceli, Center, Turkey (Türkiye), 62000
      • Faculty of Sport Sciences
  • Tunceli
    • Bitlis, Tunceli, Turkey (Türkiye), 62000
      • Munzur University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Male basketball players aged 18 to 24 years
• At least two years of regular sports experience
• Actively participating in basketball training and competition
• Voluntary participation with written informed consent

Exclusion Criteria:

• History of musculoskeletal injury or surgery within the last six months
• Presence of chronic disease or metabolic disorder
• Use of performance-enhancing drugs or hormonal supplements
• Participation in another structured training program during the study period

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Powerlifting-Based Training Group; Participants performed a structured powerlifting-based training program in addition to their regular basketball training. The intervention was conducted three days per week for six weeks. Each session lasted approximately 60 minutes and included a standardized warm-up, a powerlifting-focused main training phase, and a cool-down period. The training program emphasized the squat, bench press, and deadlift exercises performed with progressive intensity. Accessory exercises targeting lower-body strength, upper-body musculature, and core stability were included. High-intensity bodyweight exercises were also performed to enhance anaerobic capacity and neuromuscular performance. All training sessions were supervised by qualified staff.	Other: Powerlifting-Based Training; Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision.; Other: Blood Sampling and Laboratory Analysis; Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.
Other: Control Group; Participants continued their usual basketball training routines throughout the study period without any additional strength or powerlifting-based exercises.	Other: Blood Sampling and Laboratory Analysis; Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.; Other: Usual Basketball Training; Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)	Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)	Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)	Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)	Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)	Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)	Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)	Mean difference between baseline and post-intervention fasting serum insulin concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).	Baseline and post-intervention (8 weeks)
Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)	Mean difference between baseline and post-intervention fasting blood glucose concentrations, measured from venous blood samples using an automated biochemical analyzer.	Baseline and post-intervention (8 weeks)
Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)	Mean difference between baseline and post-intervention total cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.	Baseline and post-intervention (8 weeks)
Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)	Mean difference between baseline and post-intervention low-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.	Baseline and post-intervention (8 weeks)
Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)	Mean difference between baseline and post-intervention high-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.	Baseline and post-intervention (8 weeks)
Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL)	Mean difference between baseline and post-intervention triglyceride concentrations, measured from venous blood samples using an automated biochemical analyzer.	Baseline and post-intervention (8 weeks)

Collaborators and Investigators

• Sponsor: Ramazan Erdoğan

Study record dates

Study Major Dates

• Study Start (Actual): January 10, 2025
• Primary Completion (Actual): June 15, 2025
• Study Completion (Actual): October 15, 2025

Study Registration Dates

• First Submitted: December 29, 2025
• First Submitted That Met QC Criteria: February 4, 2026
• First Posted (Actual): February 9, 2026

Study Record Updates

• Last Update Posted (Actual): February 9, 2026
• Last Update Submitted That Met QC Criteria: February 4, 2026
• Last Verified: January 1, 2026

More Information

Terms related to this study

• Keywords: Strength Training; Basketball; Powerlifting
• Additional Relevant MeSH Terms: Investigative Techniques; Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Blood Specimen Collection
• Other Study ID Numbers: E-31679287-663.05-523405 (Other Identifier: Ethics Committee of Dicle University)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: Individual participant data will not be shared due to ethical restrictions, participant confidentiality concerns, and the absence of participant consent for data sharing beyond the scope of this study.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No