ADOLESCENTS IMAGING USING fMRI: Feasibility Study (ADO IMAGE)

April 17, 2026 updated by: Etablissement Public de la Sante Mentale de la Somme

Feasibility Study Using Functional Magnetic Resonance Imaging (fMRI) on Bordeline Personality Disorders in Adolescents

Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents with BPD. This study aims to increase knowledgements related to neural correlates of BPD and clinical disorders.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

21

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Female adolescents meeting DIB-R criteria for BPD group
  • Female adolescents meeting kSADS-PL for ADHD group
  • Female adolescents without any psychologic disorders

Exclusion Criteria:

  • Any medical history with head trauma, chronic neurologic disease, any contraindications for fRMI, claustrophobia or pregnancy.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Diagnostic
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Healthy adolescent girl volunteers
The participants will follow the same study plan
Diagnostic test: functional magnetic resonance imaging (fMRI)
Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.
Other: Adolescent girls with borderline personality disorder
The participants will follow the same study plan
Diagnostic test: functional magnetic resonance imaging (fMRI)
Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.
Other: Adolescent girls with Attention Deficit Hyperactivity Disorder
The participants will follow the same study plan
Diagnostic test: functional magnetic resonance imaging (fMRI)
Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
MRI-Acquired Activation Mapping
Time Frame: 2 years
Establishment of activation maps by statistical analysis of local signal variations to locate functional regions essential to motor skills and language.
2 years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Feasibility of this study
Time Frame: 2 years
Pilot feasibility study with a small sample size
2 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Etablissement Public de la Sante Mentale de la Somme

Collaborators

Centre Hospitalier Universitaire, Amiens

Investigators

  • Principal Investigator: Jean Marc GUILE, Professor, EPSM de la Somme

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 8, 2024

Primary Completion (Estimated)

June 8, 2027

Study Completion (Estimated)

December 31, 2027

Study Registration Dates

First Submitted

February 18, 2026

First Submitted That Met QC Criteria

April 17, 2026

First Posted (Actual)

April 20, 2026

Study Record Updates

Last Update Posted (Actual)

April 20, 2026

Last Update Submitted That Met QC Criteria

April 17, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2022-A00741-42

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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