ST266 Versus Standard Care In Treating Partial Thickness Burns

Inclusion Criteria:

• A signed IRB (Institutional Review Board)- approved Informed Consent Form;
• 18 - 65 years of age;
• Two (2) similar, non-contiguous, partial-thickness burn wounds between 50 cm2 and 250 cm2 in area with blisters removed in a Total Body Surface Area(TBSA) burn of less than or equal to 40% TBSA;
• Burns must be thermal burns of flame or scald etiology;
• Patient must present to the burn center within 8 hours of injury;
• Normal creatinine and bilirubin levels;
• If capable of bearing children, patient must be using a medically accepted means of birth control and have a negative serum pregnancy test;
• Willing to participate in the clinical study and comply with the requirements of the trial.

Exclusion Criteria:

• The two (2) chosen wounds must not be full-thickness (extending through the dermis into the subcutaneous tissue);
• Thermal burn from chemical, electrical or radiation causes;
• Neither the study wound nor the comparator wound can be < 50 cm2 or >250 cm2 in size and cannot be on the face or hands;
• Patients with significant pulmonary injury, i.e., smoke inhalation injury requiring ventilator support;
• Patients with diabetes;
• Patients with any immune deficiency including current treatment with corticosteroid medication, chemotherapeutic agents, anti-viral therapy, or concurrent radiation therapy within 30 days of signing the informed consent;
• Abnormal bilirubin, liver function studies (i.e., Alanine transaminase (ALT); Aspartate transaminase (AST)> 2.0 times normal);
• Abnormal serum creatinine, receiving hemodialysis or peritoneal dialysis;
• Active cancer or a history of cancer in the 5 years prior to signing the informed consent form (history of basal cell carcinoma is allowed);
• Psychiatric condition or substance abuse which in the Investigator's opinion may pose a threat to patient compliance;
• History of non-compliance with treatment or clinical visit attendance.
• Patients whose burns were previously treated with anything other than ice, cold water or dry dressing.
• Participation in an investigational trial within 30 days of study entry.