- ICH GCP
- Registr klinických studií v USA
- Klinická studie NCT02738086
Physical Activity Behavior Change for Older Adults After Dysvascular Amputation (PABC)
Physical Activity Behavior Change for Older Veterans After Dysvascular Amputation
Přehled studie
Postavení
Detailní popis
This pilot study will assess the feasibility of using the Physical Activity Behavior Change(PABC) intervention for Veterans with dysvascular lower limb amputation. In addition, preliminary efficacy of the PABC intervention will be assessed using a two-group randomized cross-over design. Testing will occur at baseline (pre-intervention), three months (end of intervention), and six months. The primary aim is to determine feasibility of using the PABC intervention with Veterans who have dysvascular amputation by measuring:
- participant retention
- dose goal attainment
- participant acceptability
- safety The secondary aim is to preliminary assess efficacy of the PABC intervention by measuring accelerometer-based physical activity and self-report disability effect sizes.
Typ studie
Zápis (Aktuální)
Fáze
- Nelze použít
Kontakty a umístění
Studijní místa
-
-
Colorado
-
Aurora, Colorado, Spojené státy, 80045
- Rocky Mountain Regional VA Medical Center, Aurora, CO
-
-
Kritéria účasti
Kritéria způsobilosti
Věk způsobilý ke studiu
Přijímá zdravé dobrovolníky
Pohlaví způsobilá ke studiu
Popis
Inclusion Criteria:
- Lower limb amputation 1-5 years prior to enrollment
- Type 2 Diabetes Mellitus and/or
- Peripheral Artery Disease
- Ambulatory using a lower limb prosthesis
- English speaking
Exclusion Criteria:
- Traumatic or cancer-related etiology of the lower limb amputation
Unstable heart condition, including:
- unstable angina
- uncontrolled cardiac dysrhythmia
- acute myocarditis
- acute pericarditis
- Uncontrolled hypertension
- Acute systemic infection
- Prisoner
- Decisionally challenged volunteers
- Cancer
- Recent cerebral vascular accident (within two years)
- lower extremity wound or ulcer that limits ability to ambulate
Studijní plán
Jak je studie koncipována?
Detaily designu
- Primární účel: Léčba
- Přidělení: Randomizované
- Intervenční model: Crossover Assignment
- Maskování: Singl
Zbraně a zásahy
Skupina účastníků / Arm |
Intervence / Léčba |
---|---|
Experimentální: Early PABC Intervention
GROUP 1 will participate in the Physical Activity Behavior Change (PABC) intervention phase during the first 3 months.
GROUP 1 will then participate in a non-exercise control phase during the second 3 months.
|
Home-based weekly sessions (30 min) using behavior change methods for promoting physical activity.
Sessions will occur using home-based computer tablets for real-time video interface between the participant and therapist.
Participants will wear wrist-mounted activity sensors with direct physical activity feedback during the intervention period to allow for behavioral feedback and action planning.
Home-based weekly sessions (30 min) using behavior change methods for promoting physical activity.
Sessions will occur using home-based computer tablets for real-time video interface between the participant and therapist.
Participants will wear wrist-mounted activity sensors with direct physical activity feedback during the intervention period to allow for behavioral feedback and action planning
|
Experimentální: Wait-List Control Intervention
GROUP 2 will participate in a non-exercise control phase during the first 3 months.
GROUP 2 will then participate in the Physical Activity Behavior Change (PABC) intervention phase in the second 3 months.
|
Home-based weekly sessions (30 min) using behavior change methods for promoting physical activity.
Sessions will occur using home-based computer tablets for real-time video interface between the participant and therapist.
Participants will wear wrist-mounted activity sensors with direct physical activity feedback during the intervention period to allow for behavioral feedback and action planning.
Home-based weekly sessions (30 min) using behavior change methods for promoting physical activity.
Sessions will occur using home-based computer tablets for real-time video interface between the participant and therapist.
Participants will wear wrist-mounted activity sensors with direct physical activity feedback during the intervention period to allow for behavioral feedback and action planning
|
Co je měření studie?
Primární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
---|---|---|
Retention Rate
Časové okno: 3 months
|
Retention rate will be measured as the percent of participants enrolled in the intervention who complete the intervention.
|
3 months
|
Dose Goal Attainment
Časové okno: 3 months
|
Dose goal attainment will be measured as the percent of participants in the intervention phase of the study who meet the dose goal of an average 3% increase in daily steps.
|
3 months
|
Acceptability
Časové okno: 3 months
|
Acceptability will be measured using the mean score of the Intrinsic Motivation Inventory - Interest / Enjoyment Subscale.
The scores range from 1 to 7, with higher numbers indicating higher acceptability, and a null value of 5.0.
|
3 months
|
Study-Related Adverse Events
Časové okno: 3 months
|
Safety will be assessed as differences in rates of study-related adverse events between GROUP 1 and GROUP 2 during the first three months, when GROUP 1 is in the intervention phase and GROUP 2 is in the non-intervention control phase.
|
3 months
|
Sekundární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
---|---|---|
Accelerometer-Based Physical Activity
Časové okno: 3 months
|
Physical activity counts will be measured using a waist-mounted accelerometer-based physical activity monitor (Actigraph).
The outcome will be average daily physical activity counts.
|
3 months
|
Late Life Function and Disability Scale, Frequency
Časové okno: 3 months
|
The Late Life Function and Disability Scale (LLFDSI) will be used to assess the participant-reported disability at each test point.
Scores range from 0 to 100, with higher scores indicating higher disability.
|
3 months
|
Accelerometer-Based Physical Activity
Časové okno: 6 months
|
Physical activity counts will be measured using a waist-mounted accelerometer-based physical activity monitor (Actigraph).
The outcome will be average daily physical activity counts.
|
6 months
|
Late Life Function and Disability Scale, Frequency
Časové okno: 6 months
|
The Late Life Function and Disability Scale (LLFDSI) will be used to assess the participant-reported disability at each test point.
Scores range from 0 to 100, with higher scores indicating higher disability.
|
6 months
|
Late Life Function and Disability Scale, Limitation
Časové okno: 3 months
|
The Late Life Function and Disability Scale (LLFDSI) will be used to assess the participant-reported disability at each test point.
Scores range from 0 to 100, with higher scores indicating higher disability.
|
3 months
|
Late Life Function and Disability Scale, Limitation
Časové okno: 6 months
|
The Late Life Function and Disability Scale (LLFDSI) will be used to assess the participant-reported disability at each test point.
Scores range from 0 to 100, with higher scores indicating higher disability.
|
6 months
|
Spolupracovníci a vyšetřovatelé
Publikace a užitečné odkazy
Termíny studijních záznamů
Hlavní termíny studia
Začátek studia (Aktuální)
Primární dokončení (Aktuální)
Dokončení studie (Aktuální)
Termíny zápisu do studia
První předloženo
První předloženo, které splnilo kritéria kontroly kvality
První zveřejněno (Odhad)
Aktualizace studijních záznamů
Poslední zveřejněná aktualizace (Aktuální)
Odeslaná poslední aktualizace, která splnila kritéria kontroly kvality
Naposledy ověřeno
Více informací
Termíny související s touto studií
Klíčová slova
Další relevantní podmínky MeSH
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