Benefits of a Mild Body Exercise in Parkinson's Disease

Benefits of a Mild Body Exercise in Parkinson's Disease

Patrocinadores

Patrocinador principal: University of Kansas Medical Center

Fuente University of Kansas Medical Center
Resumen breve

The purpose of this study is to learn the effects of two mild body exercises on quality of life, non-motor symptoms, anxiety, depression, fatigue, sleep quality, cognition, and executive function on people with Parkinson's Disease (PD).

Estado general Recruiting
Fecha de inicio July 5, 2017
Fecha de Terminación July 2020
Fecha de finalización primaria December 2019
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
Parkinson's Disease Sleep Scale (PDSS-2) Change from Baseline to Week 12
Resultado secundario
Medida Periodo de tiempo
Parkinson's Disease Questionnaire (PDQ-39) Change from Baseline to Week 12
Non Motor Symptom Questionnaire (NMSQuest) Change from Baseline to Week 12
Geriatric Anxiety Scale (GAS-10) Change from Baseline to Week 12
Geriatric Depression Scale (GDS-15) Change from Baseline to Week 12
Parkinson Fatigue Scale (PFS-16) Change from Baseline to Week 12
Parkinson's Disease-Cognitive Rating Scale (PD-CRS) Change from Baseline to Week 12
Frontal Assessment Battery (FAB-18) Change from Baseline to Week 12
Ten Point Clock Test (TPCT) Change from Baseline to Week 12
Trail Making Test parts A Change from Baseline to Week 12
Trail Making Test parts B Change from Baseline to Week 12
Unified Parkinson Disease Rating Scale (UPDRS) Change from Baseline to Week 12
IL-1beta Change from Baseline to Week 12
IL-6 Change from Baseline to Week 12
TNF-alpha Change from Baseline to Week 12
Inscripción 60
Condición
Intervención

Tipo de intervención: Behavioral

Nombre de intervención: Qigong exercise

Descripción: The Qigong exercise is a series of mild exercise movements.

Etiqueta de grupo de brazo: Intervention Group

Tipo de intervención: Behavioral

Nombre de intervención: Mild body exercise

Descripción: Participants will be taught of series of similar movements to the Qigong exercise.

Etiqueta de grupo de brazo: Control Group

Elegibilidad

Criterios:

Inclusion Criteria:

- Diagnosis of idiopathic PD

- Currently taking levodopa with some improvement in motor symptoms, and on a stable dose for a minimum of 4 weeks prior to starting the study

- Hoehn & Yahr stage I to III (mild to moderate PD)

Exclusion Criteria:

- Mini Mental State Examination (MMSE) score < 24

- Central neurological diseases other than PD or prior major head trauma with loss of consciousness, including other forms of parkinsonism, uncontrolled or significant cardiovascular diseases, orthopedic or medical problems that would interfere with gait

- Being primarily wheelchair bound

- Deep brain stimulation

- Expected change in PD medications over the course of the study

- Subjects with MRI contraindications such as pacemaker, aneurysm clips, artificial heart valves, metal fragments, foreign objects or claustrophobia.

Género: All

Edad mínima: 45 Years

Edad máxima: 70 Years

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
Wen Liu, PhD Principal Investigator University of Kansas Medical Center
Contacto general

Apellido: Sanghee Moon

Teléfono: (913) 588-4565

Email: [email protected]

Ubicación
Instalaciones: Estado: University of Kansas Medical Center
Ubicacion Paises

United States

Fecha de verificación

May 2019

Fiesta responsable

Tipo: Sponsor

Tiene acceso ampliado No
Condición Examinar
Número de brazos 2
Grupo de brazo

Etiqueta: Intervention Group

Tipo: Experimental

Descripción: Participation in the intervention group will involve a total of 14 visits over about 14 weeks to the study site, and then a 6-month follow-up evaluation. Participants will learn and practice the Qigong exercise during the study.

Etiqueta: Control Group

Tipo: Sham Comparator

Descripción: Participation in the intervention group will involve a total of 14 visits over about 14 weeks to the study site, and then a 6-month follow-up evaluation. Participants will learn and practice a mild body exercise during the study.

Información de diseño del estudio

Asignación: Randomized

Modelo de intervención: Parallel Assignment

Propósito primario: Other

Enmascaramiento: None (Open Label)

Fuente: ClinicalTrials.gov