- ICH GCP
- Registre américain des essais cliniques
- Essai clinique NCT01129804
Network Support for Alcohol Treatment 2
Network Support for Alcohol Treatment: Mechanisms and Effectiveness
The Network Support project is part of an ongoing effort to improve treatment for alcohol dependent patients. The Network Support Project is designed to help patients change their social network from one that reinforces drinking behavior to one that reinforces sobriety.
160 patients will be assigned to one of two treatments. Each of the treatments will last 12 weeks. The first is a Network Support (NS) treatment designed to help patients develop new acquaintances and social networks. It is expected that alcohol dependent patients will benefit from increasing their contact with non-drinking people. This NS condition will be compared to a packaged CBT program for alcoholics (PCBT) that is designed to teach a number of skills to help people stop drinking, but does not address social networks per se.
In order to better understand what is happening to the investigators patients, the investigators will be using daily computerized telephone calls to ask about people's experiences. This will be done both before and after treatment. Patients will also be asked to participate in follow-up interviews every 3 months for 2 years following the end of treatment.
Aperçu de l'étude
Statut
Les conditions
Intervention / Traitement
Type d'étude
Inscription (Réel)
Phase
- N'est pas applicable
Contacts et emplacements
Lieux d'étude
-
-
Connecticut
-
Farmington, Connecticut, États-Unis, 06030
- University of Connecticut Health Center
-
-
Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
La description
Inclusion Criteria:
- 18 yo
- meets Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for alcohol dependence
Exclusion Criteria:
- acute medical or psychiatric problems that require inpatient treatment (e.g., acute psychosis, or suicide/homicide risk)
- reading ability below the fifth grade level
- lack of reliable transportation to the treatment site, or excessive commuting distance
- inability to understand English
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
- Objectif principal: Traitement
- Répartition: Randomisé
- Modèle interventionnel: Affectation parallèle
- Masquage: Aucun (étiquette ouverte)
Armes et Interventions
Groupe de participants / Bras |
Intervention / Traitement |
---|---|
Expérimental: Network Support
Network Support treatment is aimed at helping patients change their social support network so that it supports abstinence.
In this treatment patients will be encouraged to attend AA meetings and engage in other activities that would involve non-drinkers.
These activities would be determined by the patient, with help from the therapist.
Patients would learn about methods of avoiding drinking, making new friends, and getting enjoyment from activities other than drinking.
In addition patients will learn specific skills intended to help them make new acquaintances and change their circle of friends.
|
Patients in both treatments will be taught skills to help them keep from drinking.
|
Comparateur actif: Packaged Cognitive-Behavioral Treatment
The purpose of Packaged Cognitive-Behavioral Treatment (PCBT) is to train patients in a variety of skills that they can use to keep themselves from drinking.
|
Patients in both treatments will be taught skills to help them keep from drinking.
|
Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
---|---|---|
Proportion Days Abstinent (PDA)
Délai: Every 3 months out to 2 years
|
PDA is based on data collected in each 90-day timeline follow-back assessment of daily drinking.
PDA is calculated as the number of days out of 90 in which the patient reported 0 drinks.
|
Every 3 months out to 2 years
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
---|---|---|
Social Network Change
Délai: assessed every 6 months out to 2 years, mean change over 2 years reported
|
Network Support for Abstinence.
Minimum score=0; Maximum score =1.
Higher scores indicate greater support for abstinence.
|
assessed every 6 months out to 2 years, mean change over 2 years reported
|
Collaborateurs et enquêteurs
Parrainer
Collaborateurs
Les enquêteurs
- Chercheur principal: Mark D Litt, Ph.D., UConn Health
Publications et liens utiles
Publications générales
- Litt MD, Kadden RM, Kabela-Cormier E, Petry N. Changing network support for drinking: initial findings from the network support project. J Consult Clin Psychol. 2007 Aug;75(4):542-55. doi: 10.1037/0022-006X.75.4.542.
- Litt MD, Kadden RM, Kabela-Cormier E, Petry NM. Changing network support for drinking: network support project 2-year follow-up. J Consult Clin Psychol. 2009 Apr;77(2):229-42. doi: 10.1037/a0015252.
- Litt MD, Kadden RM, Tennen H. Treatment response and non-response in CBT and Network Support for alcohol disorders: targeted mechanisms and common factors. Addiction. 2018 Aug;113(8):1407-1417. doi: 10.1111/add.14224. Epub 2018 Apr 20.
- Litt MD, Kadden RM, Tennen H, Kabela-Cormier E. Network Support II: Randomized controlled trial of Network Support treatment and cognitive behavioral therapy for alcohol use disorder. Drug Alcohol Depend. 2016 Aug 1;165:203-12. doi: 10.1016/j.drugalcdep.2016.06.010. Epub 2016 Jun 18.
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude
Achèvement primaire (Réel)
Achèvement de l'étude (Réel)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Estimation)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- 09-050
- R01AA012827 (Subvention/contrat des NIH des États-Unis)
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