The Use of LiDCOplus in Fluid Resuscitation Decision-Making
Does the Use of LiDCOplus Alter Decision-making in Fluid Prescription During Resuscitation in the Intensive Care Unit.
Unwell patients in the intensive care unit (ICU) often need supplementary fluids to be given into the bloodstream through a drip in a vein (venous cannula), however too much fluid can be harmful. It can sometimes be difficult to tell whether or not a patient will benefit from extra fluids so they are given a "fluid challenge", whereby a small volume of fluid is given quickly into the cannula and the change in their status is noted. If the patient's condition improves, this suggests that the patient is "fluid responsive" and needs more fluid.
A LiDCOplus haemodynamic monitor is a device used in the ICU to estimate the amount of blood ejected from the heart on each heartbeat using pressure readings obtained from a tube placed in one of the patient's arteries (arterial line).
The investigators aim to determine whether or not the use of this device called makes a difference to the judgement of "fluid responsiveness" when the patient is given a fluid challenge when compared to simply using measurements of pulse and blood pressure and assessing the circulation in the patient's limbs. This will allow the investigators to determine whether or not the LiDCOplus alters the decisions made by doctors and nurses about how much fluid to give their patients and hence if it is of any benefit.
調査の概要
研究の種類
入学 (実際)
連絡先と場所
研究場所
-
-
-
Glasgow、イギリス、G4 0SF
- Glasgow Royal Infirmary
-
-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Adult patients
- Admitted to Intensive Care Unit (ICU)
- Undergoing fluid resuscitation guided by fluid challenges
- Monitored by a LiDCOplus haemodynamic monitor attached to an arterial line
Exclusion Criteria:
- Poor arterial line trace
- Moribund state
- Patient / relative refusal
- Contra-indication to fluid bolus
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 観測モデル:ケースのみ
- 時間の展望:断面図
コホートと介入
グループ/コホート |
介入・治療 |
---|---|
Patients undergoing fluid resuscitation
Adult patients in the intensive care unit (ICU) undergoing fluid resuscitation guided by the LiDCOplus haemodynamic monitor.
|
Patients in study group receive intravenous fluid bolus as part of standard fluid resuscitation.
Fluid responsiveness (i.e.
improvement in cardiac output) is estimated using both standard clinical parameters and by LiDCOplus haemodynamic monitor (with the clinician initially blinded to the latter) before a final decision about fluid responsiveness is made.
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Fluid responsiveness decisions changed by use of LiDCOplus
時間枠:10 minutes
|
Proportion of decisions about fluid management changed by knowledge of the change in stroke volume post fluid challenge, as derived by LiDCOplus haemodynamic monitor.
|
10 minutes
|
協力者と研究者
捜査官
- 主任研究者:James A Patterson, MBChB、NHS Greater Glasgow and Clyde
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
LiDCOplus haemodynamic monitorの臨床試験
-
Children's Mercy Hospital Kansas CityGabi SmartCare招待による登録
-
Medtronic Cardiac Rhythm and Heart Failure募集
-
Erasmus Medical Center募集
-
Lady Davis InstituteCarebook Technologies Inc.わからない血管疾患 | コロナウイルス | 呼吸器疾患 | 心臓病
-
Washington University School of MedicineThe Foundation for Barnes-Jewish Hospital完了