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Estudo piloto que aprimora a telemedicina para DM2

3 de novembro de 2026 atualizado por: Margaret Zupa, University of Pittsburgh

Estudo piloto que aprimora a prestação de cuidados de telemedicina para adultos com diabetes tipo 2 complexo

The goal of this pilot clinical trial is to assess feasibility of an intervention to deliver comprehensive, high-quality diabetes care through telemedicine among adults with type 2 diabetes who use insulin and have multiple chronic health conditions. The main question it aims to answer is:

Is an enhanced telemedicine intervention for type 2 diabetes compared to usual telemedicine care feasible?

Researchers will compare the enhanced telemedicine intervention to usual telemedicine care to see if there are differences in patient satisfaction or preliminary clinical outcomes.

Participants will complete 2-3 telemedicine diabetes care visits over approximately 6 months, as well as complete survey measures with each diabetes care visit. Patients in the intervention group will also receive additional support, including pre-visit preparation phone calls, diabetes self-management education and support aligned with their visits, and post-visit follow-up calls.

Visão geral do estudo

Descrição detalhada

This pilot study will compare an intervention to deliver high-quality diabetes care through telemedicine for adults with type 2 diabetes who have additional chronic health conditions and use insulin with usual telemedicine care. The investigators will assess feasibility, patient satisfaction, and preliminary clinical outcomes.

Fifty adults will be recruited from primary care practices. Once patients are confirmed eligible, they will be consented and enrolled. Patients will be randomized to the intervention arm or usual telemedicine care, stratified by age (above or below 65 years) and rurality, as these factors are associated with technological literacy and broadband access, which may impact telemedicine use and outcomes. Both groups will complete baseline survey measures and baseline clinical data will be collected via chart review. As this is a pragmatic pilot trial, intervention components will be delivered by usual clinical providers and staff for the intervention group. The telemedicine care intervention will include 2-3 synchronous visits with endocrinology providers over 6 months plus additional visits with multidisciplinary providers on an individualized basis. Telemedicine care will proceed as usual for the control group.

The investigators will focus pilot trial outcomes on standard metrics to assess feasibility for a future large trial. The investigators will also measure preliminary clinical outcomes.

Tipo de estudo

Intervencional

Inscrição (Real)

43

Estágio

  • Não aplicável

Contactos e Locais

Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.

Locais de estudo

    • Pennsylvania
      • Pittsburgh, Pennsylvania, Estados Unidos, 15213
        • University of Pittsburgh

Critérios de participação

Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.

Critérios de elegibilidade

Idades elegíveis para estudo

18 anos a 80 anos (Adulto, Adulto mais velho)

Aceita Voluntários Saudáveis

Não

Gêneros Elegíveis para o Estudo

Tudo

Descrição

Inclusion Criteria:

  • adults 18 years or older
  • Diagnosis of type 2 diabetes based on abbreviated ICD-10 code E11.X in medical record or self-report
  • HbA1c greater than or equal to 8% based on most recent value at time of recruitment
  • Patients must own or have access to a smart phone, tablet, or home computer with data or internet connection that allows access to video-based visits
  • Patient must use insulin
  • Patients must have >2 comorbid chronic health conditions
  • Be able to provide informed consent
  • Reside in Pennsylvania

Exclusion criteria:

  • Age over 80 based on date of birth in electronic medical record

  • Visit with an endocrinologist in the prior 1 years

  • Dementia, ESRD, malignancy based on abbreviated ICD-10 codes below in medical record or self-report of associated condition

    • Dementia: A81.0x, F01.5x, F02.8x, F03.9x, F10.27, F10.97, F13.27, F13.97, F18.97, F19.17, F19.27, F19.97, G30.x, G31.0x, G31.1, G31.83, G31.85
    • Malignancy, except non-melanoma skin cancer: C00.x-C14.x, C15.x-C26.x, C3x.xx, C40.xx-C41.x, C43.x, C4A.xx, C45.x-C49.xx, C50.xxx, C51.x-C58, C60.x-C63.x, C64.x- C68.x, C69.xx-C72.x, C73-C76.x, C7A.xx, C80.xx-C96.x (except C90.x1, C91.x1, C92.x1, C93.x1, C94.x1, C95.x1)
    • ESRD N18.6
  • Type 1, gestational, or other diabetes based on abbreviated ICD-10 codes below in medical record or self-report of associated condition

    • Type 1 diabetes: E10.X
    • Gestational diabetes: O24.X, E08.X
    • Other diabetes: E09.X, E13.2
  • Pregnant or planning to become pregnant in next 6 months

  • Currently enrolled in another diabetes management intervention study

Plano de estudo

Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.

Como o estudo é projetado?

Detalhes do projeto

  • Finalidade Principal: Pesquisa de serviços de saúde
  • Alocação: Randomizado
  • Modelo Intervencional: Atribuição Paralela
  • Mascaramento: Nenhum (rótulo aberto)

Armas e Intervenções

Grupo de Participantes / Braço
Intervenção / Tratamento
Experimental: Enhanced Telemedicine Care

Specialty care for type 2 diabetes delivered via telemedicine by an endocrinologist, with additional multidisciplinary support from the diabetes care team.

Telemedicine-based endocrinology specialty care for type 2 diabetes with multidisciplinary diabetes care team support including pre-visit preparation, in-visit support and self-management education, and post-visit follow-up.

Comparador Ativo: Usual Care

Specialty care for type 2 diabetes delivered via telemedicine by an endocrinologist following usual clinical care protocols.

Routine telemedicine-based endocrinology specialty care for type 2 diabetes, generally consisting of synchronous virtual visit with an endocrinologist and additional support including self-management education on an individualized basis.

O que o estudo está medindo?

Medidas de resultados primários

Medida de resultado
Descrição da medida
Prazo
Recruitment percentage
Prazo: 12 months

Percent of eligible patients approached who are enrolled

12 months
Loss to follow up
Prazo: 6 months

Percent of enrolled patients who do not complete study, defined as not completing at least 2 study visits and associated surveys

6 months

Medidas de resultados secundários

Medida de resultado
Descrição da medida
Prazo
Recruitment rate
Prazo: 12 months

Number of patients recruited per month

12 months
Eligibility percentage
Prazo: 12 months

Percent of patients approached who are eligible

12 months
Visit attendance
Prazo: 6 months

Percent of scheduled visits completed per patient

6 months
Number of between-visit contacts
Prazo: 6 months

Number of successful and attempted patient contacts by clinicians between visits per patient

6 months
Blood glucose data availability
Prazo: 6 months

Number of telemedicine visits with blood glucose data available at visit per patient

6 months
Patient satisfaction with telemedicine diabetes care
Prazo: 6 months

Percent of patients reporting satisfied or very satisfied on a 5-point Likert scale ranging from 1 "strongly disagree" to 5 "strongly agree" with the statement "Overall, I am satisfied with the quality of service being provided via telemedicine" with higher scores indicating greater satisfaction

6 months
Diabetes Treatment Satisfaction Questionnaire-static version
Prazo: Baseline

Total score of 8-item measure of global satisfaction with diabetes treatment regimen. The static version will be used at baseline. Items 1, 4, 5, 6, 7 & 8 are summed to produce a Treatment Satisfaction score (range:0 to 36). The higher the score, the greater the satisfaction with treatment. 'Perceived frequency of hyperglycaemia' (item 2) & 'Perceived frequency of hypoglycaemia' (item 3): Both rated: 6 ('most of the time') to 0 ('none of the time'). Here, lower scores indicate blood glucose levels closer to the ideal. Higher scores indicate problems.

Baseline
Diabetes Treatment Satisfaction Questionnaire-change version
Prazo: 6 months

Total score of 8-item measure of global satisfaction with diabetes treatment regimen. The change version will be used at 6 months.Items 1, 4, 5, 6, 7 and 8 are summed to produce a Treatment Satisfaction (change) score (range: +18 to -18). The higher the score, the greater the improvement in satisfaction with treatment; the lower the score, the greater the deterioration in satisfaction with treatment. A score of 0 represents no change. Two remaining items ('Perceived change in frequency of hyperglycaemia' (item 2) and 'Perceived change in frequency of hypoglycaemia' (item 3)) are treated individually: Both rated: +3 ('much more of the time now') to -3 ('much less of the time now').

Here, negative scores indicate fewer problems with blood glucose levels. Positive scores indicate more problems than before.

6 months
T2D Diabetes Distress Core Scale
Prazo: Baseline and 6 months

Change in total score of 8-item measure of diabetes-related distress over prior month from baseline to 6 months. The Diabetes Distress Core scale is scored by averaging the value for each item, ranked from 1 to 5 scale (score range 1-5), with higher scores indicating more distress.

Baseline and 6 months
HbA1c change
Prazo: Baseline and 6 months

Change in glycemic control from baseline to 6 months

Baseline and 6 months
Prescription of guideline-based GLP-1 receptor agonist
Prazo: Baseline and 6 months

Number of patients with indications for GLP-1 receptor agonist therapy who are prescribed the indicated medication

Baseline and 6 months
Prescription of guideline-based SGLT2 inhibitor
Prazo: Baseline and 6 months

Number of patients with indications for SGLT2 inhibitor therapy who are prescribed the indicated medication

Baseline and 6 months
Retinal examination
Prazo: 6 months

Number of patients with documentation of retinal examination performed in last year in medical record

6 months
Urine protein testing
Prazo: 6 months

Number of patients with documentation of urine protein testing performed in last year in medical record

6 months
Immunization-pneumococcal
Prazo: 6 months

Number of patients with documentation of pneumococcal vaccination in medical record

6 months
Immunization-influenza
Prazo: 6 months

Number of patients with documentation of influenza vaccination in medical record

6 months

Colaboradores e Investigadores

É aqui que você encontrará pessoas e organizações envolvidas com este estudo.

Investigadores

  • Investigador principal: Margaret Zupa, MDMS, University of Pittsburgh

Datas de registro do estudo

Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados ​​pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.

Datas Principais do Estudo

Início do estudo (Real)

3 de fevereiro de 2025

Conclusão Primária (Estimado)

30 de janeiro de 2027

Conclusão do estudo (Estimado)

30 de janeiro de 2027

Datas de inscrição no estudo

Enviado pela primeira vez

13 de dezembro de 2024

Enviado pela primeira vez que atendeu aos critérios de CQ

13 de dezembro de 2024

Primeira postagem (Real)

18 de dezembro de 2024

Atualizações de registro de estudo

Última Atualização Postada (Real)

6 de novembro de 2026

Última atualização enviada que atendeu aos critérios de controle de qualidade

3 de novembro de 2026

Última verificação

1 de novembro de 2026

Mais Informações

Termos relacionados a este estudo

Palavras-chave

Outros números de identificação do estudo

  • STUDY24060062
  • K23DK135794 (Concessão/Contrato do NIH dos EUA)

Plano para dados de participantes individuais (IPD)

Planeja compartilhar dados de participantes individuais (IPD)?

SIM

Descrição do plano IPD

A deidentified dataset including limited demographic, encounter, laboratory result, clinical observations, medication orders, care utilization, and survey (intervention satisfaction, treatment satisfaction, diabetes distress) data will be created. To protect research participant identities, datasets will not include any potentially identifying participant information.

Prazo de Compartilhamento de IPD

The data will become available no later than 12 months and ending 36 months after the primary trial results are published.

Critérios de acesso de compartilhamento IPD

No access will be granted until the requesting investigator vetting process is completed including an IRB-approved protocol and data use agreement with the University of Pittsburgh.The data that may be shared includes: de-identified participant data, tables, figures, appendices, analysis plan, and protocol.

Tipo de informação de suporte de compartilhamento de IPD

  • PROTOCOLO DE ESTUDO
  • SEIVA
  • CIF

Informações sobre medicamentos e dispositivos, documentos de estudo

Estuda um medicamento regulamentado pela FDA dos EUA

Não

Estuda um produto de dispositivo regulamentado pela FDA dos EUA

Não

Essas informações foram obtidas diretamente do site clinicaltrials.gov sem nenhuma alteração. Se você tiver alguma solicitação para alterar, remover ou atualizar os detalhes do seu estudo, entre em contato com register@clinicaltrials.gov. Assim que uma alteração for implementada em clinicaltrials.gov, ela também será atualizada automaticamente em nosso site .

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