MPP Narrow QRS:Pilot Study on Multipoint Pacing in Patients With QRS Beetwen 100 and 130 Msec

Inclusion Criteria:

• Patients with EF < 35% on OPT at least 3 months and candidate to ICD
• QRS duration: 100-130 ms
• Patients willing and able to comply with study requirements
• Must indicate their understanding of the study and willingness to participate by signing an appropriate informed consent form
• Successful quadripolar LV lead implant (only for Treatment Group)

Exclusion Criteria:

• Myocardial Infarction, unstable angina within 40 days prior the enrollment
• Patients with no left ventricular contractile reserve after low dose dobutamine stress echocardiography test
• Recent cardiac revascularization (PTCA, Stent or CABG) in the 4 weeks prior to enrollment or planned for the 3 months following
• Cerebrovascular Accident (CVA) or Transient Ischemic Attack (TIA) in the 3 months prior the enrollment
• Primary valvular disease
• Unable to comply with the follow up schedule
• Less than 18 years of age
• Pregnant or are planning to become pregnant during the duration of the investigation
• Classification of Status 1 for cardiac transplantation or consideration for transplantation over the next 12 months
• Undergone a cardiac transplantation
• Life expectancy < 12 months
• Patients with permanent Atrial fibrillation
• Patients with Nyha 1