- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00438646
Oral Bacteria and Allergic Disease in Children
Oral Bacteria and History of Allergic Disease in Children: A Pilot Study
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma. This study may provide more information on why some children develop allergies and asthma.
Patients at the University of North Carolina-Chapel Hill School of Dentistry who are between 6 and 11 years of age may be eligible for this study.
Parents of participating children complete a questionnaire about the child and the child's health. The child provides a saliva sample by chewing a small piece of wax and spitting in a cup.
The saliva sample is analyzed in the laboratory for bacteria, yeast and antibodies (substances the body produces to fight germs).
...
Study Overview
Status
Conditions
Detailed Description
Study Type
Enrollment
Contacts and Locations
Study Locations
-
-
North Carolina
-
Chapel Hill, North Carolina, United States
- University of North Carolina at Chapel Hill
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
INCLUSION CRITERIA:
- Aged 6-11 years.
- Child is presenting to the UNC-CH School of Dentistry for a scheduled appointment.
- Sibling has not been enrolled.
- Parent consents to child's participation.
- Parent is willing to provide answers to a questionnaire.
- Child assents to the study.
- Child is willing and able to provide a usable saliva sample.
EXCLUSION CRITERIA:
- Child is unwilling or unable to provide a usable saliva sample.
- Parent or child is non-English speaking.
Study Plan
How is the study designed?
Design Details
Collaborators and Investigators
Publications and helpful links
General Publications
- Mannino DM, Homa DM, Akinbami LJ, Moorman JE, Gwynn C, Redd SC. Surveillance for asthma--United States, 1980-1999. MMWR Surveill Summ. 2002 Mar 29;51(1):1-13.
- Arbes SJ Jr, Gergen PJ, Elliott L, Zeldin DC. Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 2005 Aug;116(2):377-83. doi: 10.1016/j.jaci.2005.05.017.
- Liu AH, Murphy JR. Hygiene hypothesis: fact or fiction? J Allergy Clin Immunol. 2003 Mar;111(3):471-8. doi: 10.1067/mai.2003.172.
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 999907109
- 07-E-N109
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Hypersensitivity
-
Ospedale Buon Consiglio FatebenefratelliCompleted- Egg HypersensitivityItaly
-
National Institute of Allergy and Infectious Diseases...Consortium of Food Allergy ResearchCompletedMilk Hypersensitivity | Egg Hypersensitivity | Food Hypersensitivity | Peanut HypersensitivityUnited States
-
IRCCS Burlo GarofoloCompleted
-
Alton MeltonThe Cleveland ClinicActive, not recruiting
-
National Institute of Allergy and Infectious Diseases...Immune Tolerance Network (ITN)Completed
-
National Institute of Allergy and Infectious Diseases...Consortium of Food Allergy ResearchCompletedHypersensitivity | Food Hypersensitivity | Hypersensitivity, Immediate | Peanut HypersensitivityUnited States
-
University of North Carolina, Chapel HillGenentech, Inc.CompletedPeanut HypersensitivityUnited States
-
National Institute of Allergy and Infectious Diseases...Consortium of Food Allergy ResearchCompletedHypersensitivity | Food Hypersensitivity | Peanut Hypersensitivity | Immediate HypersensitivityUnited States
-
Johns Hopkins UniversityCompletedFood Hypersensitivity | Peanut Hypersensitivity | Immediate HypersensitivityUnited States
-
Allertein Therapeutics, LLCConsortium of Food Allergy ResearchCompletedHypersensitivity | Food Hypersensitivity | Peanut Hypersensitivity | Immediate HypersensitivityUnited States