Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation
Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen
Lead Sponsor: Gachon University Gil Medical Center
|Source||Gachon University Gil Medical Center|
The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.
Laparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in haemodynamic variables, regional cerebral oxygen saturation, and early postoperative cognitive function in patients undergoing laparoscopic gastrectomy in the reverse Trendelenburg position with those patients that underwent conventional open gastrectomy.
|Start Date||April 2013|
|Completion Date||July 2014|
|Primary Completion Date||July 2014|
|Study Type||Observational [Patient Registry]|
Sampling Method: Probability Sample
Inclusion Criteria: - ASA class I or II, aged 20 to 70 yrs Exclusion Criteria: - Patients with morbid obesity (body mass index > 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.
- ASA class I or II, aged 20 to 70 yrs
- Patients with morbid obesity (body mass index > 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.
Minimum Age: 20 Years
Maximum Age: 70 Years
Healthy Volunteers: No
Korea, Republic of
Type: Principal Investigator
Investigator Affiliation: Gachon University Gil Medical Center
Investigator Full Name: Hyun Jeong Kwak
Investigator Title: Associate professor
|Has Expanded Access||No|
Label: Open gastrectomy
Description: patient who undergoing open gastrectomy
Label: laparoscopic gastrectomy
Description: patient who undergoing laparoscopic gastrectomy
|Study Design Info||
Observational Model: Case-Control
Time Perspective: Prospective