Efficacy of Diode Laser in Peri-implantitis

February 12, 2015 updated by: Volkan Arisan, Istanbul University

A Randomized Clinical Trial of an Adjunct Diode Laser Application in the Treatment of Peri-implantitis.

The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis. A prospective clinical, radiographic and microbiologic split-mouth study was conducted to test the following null hypothesis; adjunct application of a diode laser, in the conventional treatment of peri-implantitis, are not associated with a statistically significant difference regarding the microbial counts, marginal bone loss and peri-implant parameters.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Efficacy of a diode laser (DL) in peri-implantitis was investigated. 48 implants diagnosed with peri-implantitis were included. In addition to the conventional scaling and debridement, random 24 implants were lased by a DL. Periodontal indexes, microbiologic specimens and radiographs were used for assessment. Baseline parameters were similar between groups. After six months laser group revealed higher MBL than the control group. Microbiota of the implants were found unchanged after one month. DL appears to have no additional positive influence on the peri-implantitis treatment.

Study Type

Interventional

Enrollment (Actual)

10

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Capa
      • Istanbul, Capa, Turkey, 34093
        • Department of Oral Implantology, Faculty of Dentistry, Istanbul University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • 18 years and older
  • No local and systemic health problems prohibit the study interventions
  • Bi-lateral implants with peri-implantitis diagnosis

Exclusion Criteria:

  • Local and systemic health problems prohibiting the study interventions

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Conventional peri-implantitis treatment
Peri-implantitis treatment according to the Cumulative interceptive supportive (CIST) therapy.
Procedure: Conventional peri-implantitis treatment
Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.
Other Names:
  • CIST treatment protocol
Experimental: DL application in peri-implantitis
Adjunct Diode Laser application.
Device: DL application in peri-implantitis
Diode laser application in the diseased implants.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Bacterial counts
Time Frame: One month
Bacterial load around the the diseased implants will be determined at the initiation of the study. The assessment will be performed after one months
One month

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Marginal Bone loss
Time Frame: Six months
The marginal bone loss around the diseased implants will be assessed after six months to analyse any bone level change.
Six months

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Peri-implant health indexes
Time Frame: one and six months
Bleeding on probing, probing depth and plaque index which determined at the initiation of the study will be re-evaluated after one and six months to asees the effect of the variables
one and six months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istanbul University

Collaborators

Istanbul University Research Fund

Investigators

  • Study Chair: Volkan Arısan, Ass.Prof.Dr., Istanbul University, Faculty of Dentistry
  • Study Director: Cuneyt Karabuda, Prof.Dr., Istanbul University, Faculty of Dentistry

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2010

Primary Completion (Actual)

July 1, 2014

Study Completion (Actual)

July 1, 2014

Study Registration Dates

First Submitted

September 16, 2014

First Submitted That Met QC Criteria

February 12, 2015

First Posted (Estimate)

February 13, 2015

Study Record Updates

Last Update Posted (Estimate)

February 13, 2015

Last Update Submitted That Met QC Criteria

February 12, 2015

Last Verified

February 1, 2015

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IstanbulU

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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