Irony Comprehension Ability of Chinese Speaking Patients With TBI

A Preliminary Study on Irony Comprehension Ability of Chinese Speaking Patients With Traumatic Brain Injury

This study aims at understanding irony comprehension ability of Chinese speaking patients with TBI through a series of self-made stories. Each story contains two characters having a conversation, and one of them would give a figurative (which is, ironic) or literal statement at the end of the story. The participants are asked to figure out its meaning.

Study Overview

• Status: Unknown
• Conditions: Traumatic Brain Injury
• Intervention / Treatment: Behavioral: Watching ironic stories

Detailed Description

The investigator plans to recruit TBI patients and control group whose gender and age accord with them, 15 people in each group. They would be asked to read the materials mentioned above displaying by a computer. It may take 30 minutes per time, and every participants only do once.

• Study Type: Observational
• Enrollment (Anticipated): 120

Contacts and Locations

• Study Contact: Name: Hsin-Tzu Tseng; Phone Number: +886 978108036; Email: s0480052@gmail.com

Study Locations

• Taiwan
  • Taipei, Taiwan, 802
    • Recruiting
    • National Taiwan University Hospital
    • Contact: Hsin-Tzu Tseng; Phone Number: +886 978108036; Email: s0480052@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

NTUH

Description

Inclusion Criteria:

• Above 20 years old
• Chinese speaking people
• Diagnosed as TBI patients for over 6 months
• Having no other neurological and mental related problems
• Able to read with or without assistive device like glasses

Exclusion Criteria:

• Addicted to alcohol or drug morbid and postmorbid
• Having any communication disorders

Study Plan

How is the study designed?

Number of groups / cohorts

5

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
TBI group; 15 people in this group. Each should be post TBI for 6 months.	Behavioral: Watching ironic stories; All the participants would be asked to watch a series of self-made stories which are figurative or literal. They have to figure out what is the real meaning of the character's statement. The whole procedure will be done with a computer.
Control group to TBI; 15 people in this group. Their gender and age accord with TBI group.	Behavioral: Watching ironic stories; All the participants would be asked to watch a series of self-made stories which are figurative or literal. They have to figure out what is the real meaning of the character's statement. The whole procedure will be done with a computer.
Aging group 1- 20 to 39; Normal people whose age range from 20 to 39.	Behavioral: Watching ironic stories; All the participants would be asked to watch a series of self-made stories which are figurative or literal. They have to figure out what is the real meaning of the character's statement. The whole procedure will be done with a computer.
Aging group 2- 40 to 59; Normal people whose age range from 40 to 59.	Behavioral: Watching ironic stories; All the participants would be asked to watch a series of self-made stories which are figurative or literal. They have to figure out what is the real meaning of the character's statement. The whole procedure will be done with a computer.
Aging group 3- above 60; Normal people whose age are above 60.	Behavioral: Watching ironic stories; All the participants would be asked to watch a series of self-made stories which are figurative or literal. They have to figure out what is the real meaning of the character's statement. The whole procedure will be done with a computer.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
TBI group gets lower scores	We assume that TBI group can't comprehend ironic statement as well as their control group. Therefore, they may get lower score than their normal- health control group.	2 months

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital
• Investigators: Study Chair: Yu-Chun Chih, PhD, Chung Shan Medical University

Publications and helpful links

General Publications

• Angeleri R, Bosco FM, Zettin M, Sacco K, Colle L, Bara BG. Communicative impairment in traumatic brain injury: a complete pragmatic assessment. Brain Lang. 2008 Dec;107(3):229-45. doi: 10.1016/j.bandl.2008.01.002. Epub 2008 Feb 11.
• Carlomagno S, Giannotti S, Vorano L, Marini A. Discourse information content in non-aphasic adults with brain injury: a pilot study. Brain Inj. 2011;25(10):1010-8. doi: 10.3109/02699052.2011.605097.

Study record dates

Study Major Dates

• Study Start (ACTUAL): October 10, 2019
• Primary Completion (ANTICIPATED): December 31, 2019
• Study Completion (ANTICIPATED): January 31, 2020

Study Registration Dates

• First Submitted: November 10, 2019
• First Submitted That Met QC Criteria: November 10, 2019
• First Posted (ACTUAL): November 13, 2019

Study Record Updates

• Last Update Posted (ACTUAL): November 13, 2019
• Last Update Submitted That Met QC Criteria: November 10, 2019
• Last Verified: October 1, 2019

More Information

Terms related to this study

• Keywords: Irony comprehension
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Wounds and Injuries; Craniocerebral Trauma; Trauma, Nervous System; Brain Injuries; Brain Injuries, Traumatic
• Other Study ID Numbers: 201908029RINA

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No