Comprehensive Digital Archive of Cancer Imaging-Radiation Oncology( CHAVI-RO )

In this pilot project Investigators propose to create annotated image data bank of patients suffering from cancer. The system will provide India's first comprehensive platform to upload annotated images with associated medical and demographic information of a patient. It will support flexible query from the users with appropriate choice from a set of attributes and design of various query filters using a GUI. Over the proposed period of 18 months, images and records related to radiation oncology including pretreatment images of at least 500 patients would be annotated and archived in the data bank. The imaging modalities to be covered are X-RAY mammograms, SPECT, CT, CBCT, MR, PET-CT, Ultrasound, digital histopathology, etc. In this phase, this study will include data sets of five types of cancers namely, breast, head and neck, brain, cervix and lung cancer.

Investigator propose to demonstrate the application of this data set in cancer research. Investigator will work on serial PET-CT based radiomics of breast and cervix cancer patients to extract appropriate features and correlate them with clinico-pathological variants.

Study Overview

• Status: Completed
• Conditions: All Cancer

• Study Type: Observational
• Enrollment (Actual): 500

Contacts and Locations

Study Locations

• India
  • West Bengal
    • Kolkata, West Bengal, India, 700160
      • Sanjoy Chatterjee

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All Patients undergoing radiotherapy in the dept of radiotherapy, Tata Medical Center.

Description

Inclusion Criteria:

1. Patients undergoing radiotherapy planned with volumetric imaging.

-

Exclusion Criteria:

• Informed Consent not given

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Main Cohort; All patients are undergoing radiotherapy in Tata Medical Center

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients with complete data safe.	Count of patients with complete radiological, pathological and demographic information in the CHAVI RO database.	18 months

Collaborators and Investigators

• Sponsor: Tata Medical Center

Study record dates

Study Major Dates

• Study Start (Actual): August 31, 2018
• Primary Completion (Actual): February 28, 2021
• Study Completion (Actual): February 28, 2021

Study Registration Dates

• First Submitted: January 29, 2020
• First Submitted That Met QC Criteria: January 29, 2020
• First Posted (Actual): January 31, 2020

Study Record Updates

• Last Update Posted (Actual): December 17, 2021
• Last Update Submitted That Met QC Criteria: December 2, 2021
• Last Verified: December 1, 2021

More Information

Terms related to this study

• Keywords: Carcinoma; Artificial Intelligence; Radiology; Image Processing; Molecular Biology; Radiomics; Radiation Oncology; Big Data; Data Analytics Center; Medical Physics
• Additional Relevant MeSH Terms: Neoplasms
• Other Study ID Numbers: EC/GOVT/24/IRB23

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No