Relationship Between Muscle Strength and Physical Function in ICU

November 23, 2021 updated by: Anne-Françoise Rousseau, University of Liege

Analysis of the Relationship Between Muscle Strength and Physical Function in ICU Survivors

This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry. Physical function is assessed using the validated ICU mobility scale.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

93

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Belgium
      • Liège, Belgium, 4000
        • University Hospital of Liege

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

The study includes all critical ill patients staying in ICU for at least 48 hours. They are screened as soon as they are collaborative.

Description

Inclusion Criteria:

  • ICU stay of at least 48h
  • Collaborative (RASS score -1 to +1)

Exclusion Criteria:

  • Refusal
  • Coma
  • Non collaborative
  • Hemi / tetra paresis or plegia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Quadriceps strength
Time Frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge
Quadriceps maximal isometric strength measured using dynamometry
as soon as collaborative during ICU stay and up to 1 month following ICU discharge
Handgrip strength
Time Frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge
Grip maximal isometric strength measured using dynamometry
as soon as collaborative during ICU stay and up to 1 month following ICU discharge
ICU mobility scale
Time Frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge
Ranking the patient on the scale according to his/her physical capacity. ICU mobility scale is a 10 points scale: 0 means the patient is lying in bed, 10 means the patient is able to walk independently
as soon as collaborative during ICU stay and up to 1 month following ICU discharge

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Liege

Investigators

  • Principal Investigator: Anne-Françoise Rousseau, MD, PhD, University Hospital of Liege
  • Principal Investigator: Isabelle Kellens, PT, PhD, University Hospital of Liege

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2018

Primary Completion (Actual)

December 31, 2019

Study Completion (Actual)

November 1, 2021

Study Registration Dates

First Submitted

February 18, 2020

First Submitted That Met QC Criteria

February 22, 2020

First Posted (Actual)

February 25, 2020

Study Record Updates

Last Update Posted (Actual)

November 26, 2021

Last Update Submitted That Met QC Criteria

November 23, 2021

Last Verified

November 1, 2021

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MSF

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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