Colonic Duplication; Two Cases Report and Review of Literature

Duplicated colon appendix are infrequent detected during surgical exploration. For Diagnosed cases, excision of the duplicated part is indispensable, due to risk of malignancy.

Study Overview

• Status: Completed
• Conditions: Colonic Diseases
• Intervention / Treatment: Other: colonic surgery

Detailed Description

Alimentary tract duplication represents(ATD) 0.2% of all pediatric congenital malformations Which affect all gastrointestinal tracts (GIT) from the mouth to the anus.

ATD more common in with no familial or racial predilection. The ileum is the most common site (30%-35%) and the colon is the least common site (7%-20%).

The transverse colon is the most common site for colonic duplication. The duplicated part of GIT maybe in the mesenteric or anti-mesenteric side. It may has same vascular supply and mesentry or not(reported only in small bowel)..

Communication between the anomalous and actual enteric lumens may or may not be present.

Here in, two cases of colonic and anal duplication add to the knowledge with review of literature of duplicated colon in children.

• Study Type: Observational
• Enrollment (Actual): 2

Contacts and Locations

Study Locations

• Egypt
  • Assiut, Egypt, 71111
    • Mohammed Hamada Takrouney

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 day to 18 years (ADULT, CHILD)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients age group from 1 day till 18 years

Description

Inclusion Criteria:

1. Pediatric patients till age of 18 years old
2. All patients diagnosed with duplicated colon with or without symptoms
3. Patients with duplicated colon and other associated colorectal anomalies

Exclusion Criteria:

1. Patients > 18 years with duplicated colon
2. All patients with duplication cyst

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Post duplicated colon resection constipation by Bristol stool scale	Bristol stool form scale it range from type 1 (separate hard lumps,like hard nuts) to type 7 stool (Watery, no solid pieces ENTIRELY LIQUID)	6 months

Collaborators and Investigators

• Sponsor: Assiut University

Publications and helpful links

General Publications

• AbouZeid AA, Mohammad SA, Ibrahim SE, Fagelnor A, Zaki A. Late Diagnosis of Complete Colonic and Rectal Duplication in a Girl with an Anorectal Malformation. European J Pediatr Surg Rep. 2019 Jan;7(1):e47-e50. doi: 10.1055/s-0039-1692193. Epub 2019 Jul 5.

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 1, 2019
• Primary Completion (ACTUAL): March 1, 2020
• Study Completion (ACTUAL): March 1, 2020

Study Registration Dates

• First Submitted: March 13, 2020
• First Submitted That Met QC Criteria: March 18, 2020
• First Posted (ACTUAL): March 20, 2020

Study Record Updates

• Last Update Posted (ACTUAL): March 20, 2020
• Last Update Submitted That Met QC Criteria: March 18, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Digestive System Diseases; Gastrointestinal Diseases; Intestinal Diseases; Colonic Diseases
• Other Study ID Numbers: IRB approval number:17300179

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: this is case report and review of literature not more than this

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No