Adenovirus Keratoconjunctivitis and Ophtalmology (ADV-OPH)

Complications of Adenovirus Keratoconjunctivitis in Ophthalmologists and Orthoptists: Epidemiology and Risk Factor, a Retrospective Questionnaire Analysis

Adenovirus conjunctivitis is an epidemic disease registered as a common occupational disease for ophthalmologists and orthoptists. It can leave corneal sequelae even several years after infection.

The primary aim of the study is to investigate the prevalence of these sequelae in the at-risk population of ophthalmologists and orthoptist.

Secondary aim are to describe administrative procedures (occupational disease declaration and sick leave),infections characteristics; and risk factors.

Study Overview

• Status: Unknown
• Conditions: Adenoviral Keratoconjunctivitis

Detailed Description

Adenovirus conjunctivitis is an epidemic disease registered as a common occupational disease for ophthalmologists and orthoptists. It can leave corneal sequelae even several years after infection.

The investigation tream create a nationwide anonymous retrospective questionnaire using the secure internet application REDCap® to build and manage the questionnaire addressed to ophtalmologists (interns, graduates and retirees) and orthoptists.

Investigator collect several characteristics such as general characteristics (sex, age range, profession), administrative procedure declaration (occupational disease declaration, sick leave, cessation of surgery); infection characteristics (bilaterality, season, anteriority, sequels, current therapy, professional discomfort), risk factor (refractive surgery history, wearing of eyeglasses or contact lenses, smoking, or corticosteroid therapy).

The primary aim of the study is to investigate the prevalence of these sequelae in the at-risk population of ophthalmologists and orthoptist. Secondary aim are to describe administrative procedures (occupational disease declaration and sick leave), infections characteristics; and risk factors such as a refractive surgery history, the wearing of eyeglasses or contact lenses, smoking, or corticosteroid therapy.

• Study Type: Observational
• Enrollment (Anticipated): 1000

Contacts and Locations

• Study Contact: Name: Lise Laclautre; Phone Number: 0473754963; Email: pormo_interne_drci@chu-clermontferrand.fr

Study Locations

• France
  • Clermont-Ferrand, France, 63000
    • Recruiting
    • University Hospital, Clermont-Ferrand
    • Sub-Investigator: Margaux Metzger, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

French Ophtalmologist or orthoptist

Description

Inclusion Criteria:

• Ophtalmologist or orthoptist (interns, graduates and retirees)
• French

Exclusion Criteria:

- Foreign practitionner

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
epidemiology characteristics	history of adenovirus keratoconjunctivitis; history of sequels	Day 1
general characteristics - Sex	general characteristics - Sex	Day 1
general characteristics - Age range	general characteristics - Age range	Day 1
general characteristics - Profession	general characteristics - Profession	Day 1

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
administrative procedure declaration	occupational disease declaration, sick leave, cessation of surgery and duration	Day 1
infection characteristics	bilaterality, season, anteriority, sequels, current therapy, professional discomfort	Day 1
risk factor	refractive surgery history, wearing of eyeglasses or contact lenses, smoking, corticosteroid therapy	Day 1

Collaborators and Investigators

• Sponsor: University Hospital, Clermont-Ferrand

Study record dates

Study Major Dates

• Study Start (ACTUAL): October 21, 2019
• Primary Completion (ANTICIPATED): October 1, 2022
• Study Completion (ANTICIPATED): October 1, 2022

Study Registration Dates

• First Submitted: June 2, 2020
• First Submitted That Met QC Criteria: June 3, 2020
• First Posted (ACTUAL): June 4, 2020

Study Record Updates

• Last Update Posted (ACTUAL): June 4, 2020
• Last Update Submitted That Met QC Criteria: June 3, 2020
• Last Verified: May 1, 2020

More Information

Terms related to this study

• Keywords: Epidemiology; Adenovirus; Epidemic Keratoconjunctivitis; Subepithelial infiltrates; Occupational diseases; Ophtalmologists; Orthoptists
• Additional Relevant MeSH Terms: Virus Diseases; Infections; Eye Diseases; DNA Virus Infections; Conjunctivitis; Conjunctival Diseases; Keratitis; Corneal Diseases; Adenoviridae Infections; Keratoconjunctivitis
• Other Study ID Numbers: 2020 ADV-OPH

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No