Assessment of the Anterior Loop of the IAN in a Sample of Egyptian Population Using CBCT

Assessment of the Anterior Loop of the Inferior Alveolar Nerve in a Sample of Egyptian Population Using CBCT: An Observational Cross-Sectional Study

in this study the prevalence & length of the anterior loop of the inferior alveolar nerve will be calculated and measured on retrospective CBCT patient's scans

Study Overview

• Status: Recruiting
• Conditions: Mandibular Nerve

Detailed Description

The proper knowledge of anatomical structures and their precise position is of a paramount importance for different dental specialties. The inferior alveolar nerve (IAN) canal is one of the most important anatomical landmarks in the mandible Shaban et al., 2017. By definition the inferior alveolar nerve (IAN) is a terminal division of the mandibular branch of the trigeminal nerve, it is confined within the mandibular canal and innervates all the mandibular teeth. The IAN initiates from the mandibular foramen and goes obliquely downward and forward in the ramus, and then horizontally within the body of the mandible. The IAN gives off the mental nerve, which exits the mandible through the mental foramen, supplying sensory branches to the chin, lower lip, mucous membranes and the gingiva; from the midline to about the second premolar region. It then continues its path anteriorly and turn into the mandibular incisive nerve, which innervates the mandibular canines and incisors Siddiqui et al. 2018. Before leaving the mental foramen and branching into the incisive nerve, the IAN may continue anteriorly and form an anterior loop (Al). This anterior loop is the part where the IAN directs mesially and occlusally before reversing direction and coursing distally towards the mental foramen Ragu et al., 2019. During implant planning and other surgical procedures knowing the presence of the anterior loop and its length is very crucial to avoid its injury. Specially concerning implantology where the location of the mental foramen and anterior loop determines the most distal point for implant placement in the interforaminal area; in order to avoid any injury resulting in sensory disturbances in this area Panjnoush et al., 2016 Recently, several studies have been published discussing the prevalence and length measurement of the anterior loop in many populations. However, no published researches were done on the Egyptian population. Therefore, this study is designed to assess the presence of the anterior loop and its length in a sample of Egyptian population using CBCT.

• Study Type: Observational
• Enrollment (Anticipated): 192

Contacts and Locations

• Study Contact: Name: ORASCAN Oral & Maxillofacial Imaging Centre; Phone Number: +2 0223780756; Email: Info@orascan.org
• Study Contact Backup: Name: Abdelrahman Zohny; Phone Number: 01222376888

Study Locations

• Egypt
  • Maadi
    • Cairo, Maadi, Egypt, 11728
      • Recruiting
      • Orascan
      • Contact: Abdelrahman Zohny; Phone Number: 01222376888
      • Contact: Orascan Oral & Maxillofacial Imaging Centre; Phone Number: +20223780756; Email: Info@orascan.org

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Adult Egyptian population including males & females

Description

Inclusion Criteria:

• CBCT scans of adult Egyptian patients, males and females.
• CBCT scans with unilateral or bilateral anterior mandibles; with minimum 2 mm length distal to the mental foramen

Exclusion Criteria:

• CBCT images of poor quality or artifacts interfering with the assessment of the anterior loop of IAN.
• Scans showing any pathosis in the interforaminal area (tumor or impaction).

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of the anterior loop	it will be measured using CBCT axial cuts (Ondemand 3D software)	1 month

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
length of the anterior loop	Built in measuring tools (axial cuts) in Ondemand 3D software "MPR* module"	1 month
Mesial extension of the anterior loop	Cross-sectional cuts on Ondemand 3D software "DVR** module"	1 month

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2021
• Primary Completion (Anticipated): April 1, 2022
• Study Completion (Anticipated): June 1, 2022

Study Registration Dates

• First Submitted: June 28, 2020
• First Submitted That Met QC Criteria: July 8, 2020
• First Posted (Actual): July 10, 2020

Study Record Updates

• Last Update Posted (Actual): November 5, 2021
• Last Update Submitted That Met QC Criteria: November 4, 2021
• Last Verified: July 1, 2021

More Information

Terms related to this study

• Keywords: Presence of the anterior loop of the mental nerve (branching from the inferior alveolar nerve) will be recorded & its length will be measured
• Other Study ID Numbers: ORAD 7.1.1

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No