Effectiveness of Mulligan Mobilization Technique and Core Stabilization Exercise With Knee Osteoarthritis

Investigation of the Effectiveness of Mulligan Mobilization Technique and Core Stabilization Exercises in Female Patients With Knee Osteoarthritis: A Randomized Controlled Single-Blind Study.

Osteoarthritis (OA) is a chronic disease process characterized by degeneration and inflammation in the joint cartilage and subchondral bone, synovial fluid and joint capsule. One of the most affected joints in OA is the knee joint, and the incidence of OA increases with age.

Different treatment approaches are used in the treatment of osteoarthritis. The aim of the study is to examine the effectiveness of Mulligan technique and core exercises applied to female patients with knee osteoarthritis. In addition, the investigators did not find any study examining the effect of Mulligan technique on static balance in the treatment of OA. This is the secondary aim of the study.

Study Overview

• Status: Completed
• Conditions: Exercise
• Intervention / Treatment: Other: Mulligan mobilization; Other: Core stabilization; Other: Conventional therapy

• Study Type: Interventional
• Enrollment (Actual): 42
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Denizli, Turkey, 20070
    • Pamukkale University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years to 70 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

• Being diagnosed with knee osteoarthritis
• To be in the age range of 40-70
• No lower extremity surgery in the last 6 months.
• Agree to participate in the study

Exclusion Criteria:

• Having had hip-knee replacement surgery
• Surgery planned in the last 6 months
• Having received physical therapy in the last 6 months
• Having uncontrollable hypertension and cardiac problems
• Having been diagnosed with rheumatoid arthritis

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Mulligan mobilization group; Painless movement	Other: Mulligan mobilization; Mulligan mobilization technique will be apply.
Experimental: Core stabilization group; Abdominal drawing-in maneuver	Other: Core stabilization; Core stabilization technique will be apply.
Active Comparator: conventional therapy group; Ultrasound TENS Hotpack	Other: Conventional therapy; Conventional therapy exercise will be apply.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pain assessment	Visual Analog Scale: This scale consists of a straight line with the end points defining extreme limits such as 'no pain at all', which is 0 cm, and 'pain as bad as it could be', which is 10cm.	10 minutes
Range of motion assessment	Goniometric measurement	10 minutes
muscle strength assessment	by handheld device (Commander Powertrack II brand)	10 minutes
functional level assessment	Western Ontario and McMaster Universities Arthritis Index (WOMAC)	5 minutes
aerobic endurance assessment	6 minute walk test	6 minutes
balance assessment	Stand on one leg test	5 minutes
Timed Up& Go Test	Timed Up& Go Test	5 minutes
assessment of quality of life survey	Nottingham Health Profile	5 minutes

Collaborators and Investigators

• Sponsor: Pamukkale University

Study record dates

Study Major Dates

• Study Start (Actual): August 14, 2020
• Primary Completion (Actual): February 1, 2022
• Study Completion (Actual): April 20, 2022

Study Registration Dates

• First Submitted: August 27, 2020
• First Submitted That Met QC Criteria: September 4, 2020
• First Posted (Actual): September 7, 2020

Study Record Updates

• Last Update Posted (Actual): April 21, 2022
• Last Update Submitted That Met QC Criteria: April 20, 2022
• Last Verified: April 1, 2022

More Information

Terms related to this study

• Keywords: Mulligan; Pain, Joint; Core stabilization
• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Knee
• Other Study ID Numbers: 60116787-020/48052

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No