Beta2-adrenergic System and Training

November 3, 2020 updated by: Morten Hostrup, PhD, University of Copenhagen

Trainability of the beta2-adrenergic System With Respect to Performance

This project aims to examine the trainability of the beta2-adrenergic system with respect to the individual performance response

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

30

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 45 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • 18 to 45 years of age
  • Trained individuals with a maximal oxygen uptake above 55 ml/min/kg
  • Body mass index lower than 26

Exclusion Criteria:

  • Allergy towards study drug
  • Unacceptable side effects to the study drug
  • Chronic disease deemed by the MD to interfere with the study
  • Smoking
  • Use of prescription medicine

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: SET-HIGH
High volume speed endurance training
Behavioral: Training
6 weeks of training
Drug: Formoterol
inhalation of 54 microg formoterol
Drug: Placebo
inhalation of placebo
Experimental: SET-LOW
Low volume speed endurance training
Behavioral: Training
6 weeks of training
Drug: Formoterol
inhalation of 54 microg formoterol
Drug: Placebo
inhalation of placebo

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Sprint performance
Time Frame: ½ hour after administration of formoterol or placebo
Change in power output during maximal cycling in response to formoterol
½ hour after administration of formoterol or placebo

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cycling endurance performance
Time Frame: ½ hour after administration of formoterol or placebo
Change in 4-min time trial performance in response to formoterol
½ hour after administration of formoterol or placebo

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Copenhagen

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Anticipated)

November 10, 2020

Primary Completion (Anticipated)

November 10, 2022

Study Completion (Anticipated)

November 10, 2022

Study Registration Dates

First Submitted

October 29, 2020

First Submitted That Met QC Criteria

November 3, 2020

First Posted (Actual)

November 4, 2020

Study Record Updates

Last Update Posted (Actual)

November 4, 2020

Last Update Submitted That Met QC Criteria

November 3, 2020

Last Verified

November 1, 2020

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FOREX

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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