The Angle of the Metacarpophalangeal Joint of the Thumb During Maximal Pinch Strength

The Angle of the Metacarpophalangeal Joint of the Thumb During Maximal Pinch Strength: Implications for Arthrodesis

The aim of the study is to measure the position of the metacarpophalangeal joint of the thumb during key-pinch, tripod-pinch and opposition-pinch in normal volunteers, to determine the optimal position of metacarpophalangeal joint arthrodesis.

Study Overview

• Status: Completed
• Conditions: Osteoarthritis Thumb; Post-traumatic; Arthrosis
• Intervention / Treatment: Other: measurement of range of motion and strength

Detailed Description

The aim of the study is to measure the position of the metacarpophalangeal (MCP) joint of the thumb during key-pinch, tripod-pinch and opposition-pinch in normal volunteers, to determine the optimal position of metacarpophalangeal joint arthrodesis.

The force will be measured in three positions (key-pinch, tripod-pinch and opposition-pinch). Also measured is the degree of flexion of the MCP joint of the thumb. The mobility of the MCP joint of the thumb in maximum flexion and extension will also be measured. A total of about 300 healthy volunteers will be examined, with no history of trauma or disease to tendons or joints of the thumbs and between the ages of 18 and 40. The sponsor of this study is Professor Nadine Hollevoet. Master students of medicine from the faculty of medicine and health sciences will be part of the research team.

• Study Type: Interventional
• Enrollment (Actual): 300
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Belgium
  • Oost-Vlaanderen
    • Ghent, Oost-Vlaanderen, Belgium, 9000
      • Ghent University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 40 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• age between 18 and 40 years

Exclusion Criteria:

• (previous) pathology of the joints, ligaments or tendons of the thumb

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: normal volunteers; normal volunteers between 18 and 40 years old, men and women. Measurement of the range of motion of the metacarpophalangeal joint with a goniometer and pinch strength of the thumb with a dynamometer	Other: measurement of range of motion and strength; measurement of range of motion (goniometer) and strength (dynamometer) of the metacarpophalangeal joint of the thumb

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
pinch strength of the thumb (in kilograms force)	pinch strength of the thumb in key-pinch, opposition-pinch and tripod-pinch	10 minutes
the angle of the metacarpophalangeal joint of the thumb (in degrees)	the angle of the metacarpophalangeal joint of the thumb (in degrees) during maximal force in the three pinch positions	10 minutes
range of motion of the metacarpophalangeal joint of the thumb (in degrees)	range of motion of the metacarpophalangeal joint of the thumb (in degrees) measuring maximal flexion and maximal extension of the joint	10 minutes

Collaborators and Investigators

• Sponsor: University Hospital, Ghent
• Investigators: Principal Investigator: Nadine I Hollevoet, Phd, University Hospital, Ghent

Study record dates

Study Major Dates

• Study Start (Actual): September 23, 2020
• Primary Completion (Actual): April 17, 2021
• Study Completion (Actual): April 17, 2021

Study Registration Dates

• First Submitted: April 13, 2021
• First Submitted That Met QC Criteria: April 30, 2021
• First Posted (Actual): May 6, 2021

Study Record Updates

• Last Update Posted (Estimate): January 6, 2023
• Last Update Submitted That Met QC Criteria: January 4, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis
• Other Study ID Numbers: BC-08063

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No