The Effect of Fish Oil Supplementation on Vocal Performance

The purpose of this study was to determine if use of omega-3 PUFA supplement in combination with a singer's training regimen enhances training adaptations and body composition.

Study Overview

• Status: Completed
• Conditions: Body Composition; Voice Range Profile; Reflux Symptom Index; Evaluation of Ability to Sing Easily
• Intervention / Treatment: Dietary supplement: placebo; Dietary supplement: omega-3 PUFA supplement

• Study Type: Interventional
• Enrollment (Actual): 43
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Texas
    • Waco, Texas, United States, 76798
      • Baylor University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 28 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Apparently healthy college vocal performers (male and female of all ethnicities) *Between the ages of 18-28 years
• Majoring in classical voice in the Baylor University School of Music or musical theatre in the Baylor University Department of Theatre Arts.

Exclusion Criteria:

• Previously diagnosed with a voice disorder
• Vegans
• Smokers
• Allergic to fish, shellfish or safflower oil
• Have been taking daily FO n-3 supplement within the past three months, or any supplement known to effect muscle biology (e.g. creatine).

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: omega-3 PUFA supplement; omega-3 PUFA supplement, 3.0 grams per day	Dietary supplement: omega-3 PUFA supplement; participants were instructed to take 3.0 grams per day of omega-3 PUFA supplement
Placebo Comparator: placebo; safflower oil, 3.0 grams per day	Dietary supplement: placebo; placebo

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Evaluation of Ability to Sing Easily	survey designed to aid in subject self-assessment	baseline and up to 11 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
change in Voice Range Profile	known as a phonetogram, is a representation of a participants minimum and maximum intensity levels across vocal range	baseline and up to 11 weeks
change in Body composition	height in cm, weight measured in kg. Bio-electrical impedance scale use to assess lean and body fat mass, measured in kg. Weight and height were combined to report BMI in kg/m^2	baseline and up to 11 weeks

Collaborators and Investigators

• Sponsor: Baylor University
• Investigators: Principal Investigator: LesLee Funderburk, PhD, Baylor University

Study record dates

Study Major Dates

• Study Start (Actual): February 8, 2021
• Primary Completion (Actual): May 13, 2021
• Study Completion (Actual): May 13, 2021

Study Registration Dates

• First Submitted: November 17, 2021
• First Submitted That Met QC Criteria: November 19, 2021
• First Posted (Actual): December 2, 2021

Study Record Updates

• Last Update Posted (Actual): December 2, 2021
• Last Update Submitted That Met QC Criteria: November 19, 2021
• Last Verified: November 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: 1708288-3

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No