A Study of Physical Activity in Cancer Survivors

March 19, 2026 updated by: Mayo Clinic

Improving Physical Activity in Rural Cancer Survivors

The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

100

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Minnesota
      • Albert Lea, Minnesota, United States, 56007
        • Mayo Clinic Health System in Albert Lea
      • Mankato, Minnesota, United States, 56001
        • Mayo Clinic Health System-Mankato
    • Wisconsin
      • Eau Claire, Wisconsin, United States, 54701
        • Mayo Clinic Health System-Eau Claire Clinic
      • La Crosse, Wisconsin, United States, 54601
        • Mayo Clinic Health System-Franciscan Healthcare

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Study Population

Adult Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI) Community Oncology patients entering cancer survivorship (completed initial treatment) and/or Underserved: Older (≥60 years), lower-income, rural, ethnic/racial minority, lacking access/available/acceptable forms of exercise programs

Description

Inclusion Criteria:

  • Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI), Southwest Wisconsin (SWWI), Southeast Minnesota (SEMN), or Southwest Minnesota (SWMN)
  • Any stage cancer
  • Age >= 18 years residing at a rural address (as defined by Rural America, census.gov Urban Areas 2020 metric)
  • Age ≥ 18 years residing at a rural address (as defined by Rural America, census.gov)
  • Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible.
  • Ownership of a computer/tablet/smartphone with internet access.
  • Willingness to create a google account and maintain the account for use of the Fitbit
  • Willingness and ability to attend study visits.
  • Must be able to complete semi-tandem (10 seconds), side-by-side tandem [10 seconds and short physical performance batters(SPPB)] Score of 6 or greater to qualify for virtual exercise.
  • Must be ambulatory without the use of assisted device(s).

Exclusion Criteria:

  • Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment
  • Are already performing >150 minutes/week of moderate activity or 75 min/week of vigorous physical activity
  • Cancer-free for greater than 5 years
  • Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.
  • Squamous cell or basal cell skin cancers (melanoma still eligible)
  • Stage 0/in situ vulvar/cervical cancers

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Community Oncology patients entering cancer survivorship
Patients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive bi-weekly phone calls/emails over 12 weeks. Patents also wear a Fitbit on study.
Behavioral: Physical Activity
Use Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in physical functioning using Short Physical Performance Battery
Time Frame: Baseline; 12 weeks
Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention.
Baseline; 12 weeks
Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS)
Time Frame: Baseline; 12 weeks
QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention.
Baseline; 12 weeks
Change in satisfaction using a 5-point Likert scale
Time Frame: Baseline; 12 weeks
Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program.
Baseline; 12 weeks
Rate of adherence to program based on participation in virtual exercise sessions
Time Frame: Baseline; 12 weeks
Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention.
Baseline; 12 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mayo Clinic

Investigators

  • Principal Investigator: Kaye T. Sturz, APRN, CNP, Mayo Clinic Health System in Eau Claire

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 29, 2023

Primary Completion (Actual)

April 23, 2025

Study Completion (Actual)

April 23, 2025

Study Registration Dates

First Submitted

July 26, 2023

First Submitted That Met QC Criteria

August 3, 2023

First Posted (Actual)

August 14, 2023

Study Record Updates

Last Update Posted (Actual)

March 23, 2026

Last Update Submitted That Met QC Criteria

March 19, 2026

Last Verified

October 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 23-001462
  • NCI-2023-05387 (Other Identifier: Clinical Trials Reporting Program)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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