Postoperative Analgesis for Pain Management After Thoracotomy

Comparison of Thoracal Paravertebral Block and Serratus Plan Block in Pain Management After Thoracotomy

Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy. For this purpose, systemic analgesics are used along with ultrasound-guided nerve blocks in thoracotomy pain. The effectiveness of thoracic paravertebral block and serratus plane block in the treatment of post-thoracotomy pain will be evaluated by comparing their effectiveness and complications on postoperative pain. Since the epidural spread of the thoracic paravertebral block is more effective, the effectiveness of postoperative pain relief will be more effective

Study Overview

• Status: Completed
• Conditions: Postoperative Pain; Analgesia
• Intervention / Treatment: Other: Paravertebral Block; Other: Serratus Plane Block

Detailed Description

Thoracotomy is among the most painful surgical procedures and can cause severe pain. This pain causes postoperative complications in patients who have thoracotomy surgery. Uncontrolled pain can cause respiratory and thromboembolic events. Therefore, effective pain management is important in patients undergoing thoracotomy. Investigators aim to compare the analgesic effectiveness and complications of thoracic paravertebral block and serratus anterior plane block in relieving thoracotomy pain, which is one of the most painful surgical procedures. It is aimed to compare the effectiveness and complications of thoracic paravertebral block and serratus plane block in postoperative pain control after thoracotomy. Providing pain control reduces postoperative complications and reduces hospital stay, which increases patient comfort and reduces costs. In this research, postoperative morphine consumption after block applications will be compared, and patients' analgesic needs will be evaluated according to the participants' VAS score. Post-operative 3rd, 6th, 9th, 12th, 24th. Morphine consumption will be evaluated by monitoring the hours. It will be evaluated whether there is a need for additional analgesics. During the operation, the patient's heart rate, blood pressure, saturation and temperature variable values will be closely monitored. Standard monitoring methods will be used when examining these parameters.

• Study Type: Interventional
• Enrollment (Actual): 58
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Kocaeli, Turkey
    • Kocaeli University
  • Kocaeli, Turkey
    • Nur Nazire Yucal

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• 18-75 aged patients
• American Society of Anesthesiologists Classification (ASA) I-II-III patients
• patients who scheduled elective thoracic surgery

Exclusion Criteria:

• American Society of Anesthesiologists Classification (ASA) IV-V patients
• patients with coagulopathy
• patient with infection at the injection site

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Diagnostic
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Paravertebral Block; Ultrasound (US) -guided paravertebral block (PVB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the PVB group.	Other: Paravertebral Block; Ultrasound (US) -guided paravertebral block (PVB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the PVB group.
Active Comparator: Serratus Plane Block; Ultrasound (US) -guided serratus plane block (SPB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the SPB group.	Other: Serratus Plane Block; Ultrasound (US) -guided serratus plane block (SPB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the SPB group.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Morphin consumption	Patient in both groups will provide with intravenous patient-controlled analgesia device containing morphine for postoperative analgesia	during postoperative 24 hour

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Visual Analogue Scale (VAS)	Visual Analogue Scale (VAS) requires the patient to rate their pain on a defined scale.For example , 0-10 where 0 is no pain and 10 is the worst pain imaginable	during postoperative 24 hour

Collaborators and Investigators

• Sponsor: Kocaeli University
• Investigators: Study Director: Tülay Çardaközü, Kocaeli University

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2022
• Primary Completion (Actual): July 4, 2024
• Study Completion (Actual): July 4, 2024

Study Registration Dates

• First Submitted: December 11, 2023
• First Submitted That Met QC Criteria: December 11, 2023
• First Posted (Actual): December 20, 2023

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: March 5, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Keywords: Thoracotomy; Regional Anesthesia; Paravertebral Block; Serratus Plane Block
• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Postoperative Complications; Pathologic Processes; Pain, Postoperative
• Other Study ID Numbers: KAEK/10.bI.02

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No