Validity and Reliability of a Turkish Version of MD Anderson Inventory Dysphagia Inventory

Validity and Reliability of a Turkish Version of MD Anderson Dysphagia Inventory for Neurogenic Patients

The purpose of this study is to M.D. Validity of the Turkish version of the Anderson Dysphagia Inventory for the Turkish population, reliability, and cultural adaptation.

Study Overview

• Status: Recruiting
• Conditions: Dysphagia; Neurologic Disorder
• Intervention / Treatment: Other: Turkish Version of M. D. Anderson Dysphagia Inventory

Detailed Description

Oropharyngeal dysphagia (OD) is a common finding in patients with neurogenic disorders.

Swallowing disorder can be acute or chronic in nature. For example, acute OD is observed in patients after stroke, head trauma, neurosurgical intervention, or in patients with Guillain-Barré syndrome. Chronic OD may develop in patients who do not recover after a stroke. Degenerative OD, Parkinson's disease, amyotrophic lateral sclerosis, myasthenia gravis, Huntington's disease, myotonic dystrophy type 1 and multiple sclerosis It is seen in patients with progressive neurological diseases. The prevalence of OD in neurogenic patients varies from 3% to 50% in stroke patients and up to almost 100% in patients with Huntington's disease. The OD can lead to weight loss, malnutrition, social isolation, aspiration pneumonia, and reduced health-related quality of life (QoL). Some studies have reported that dysphagia-specific QoL is weakly associated with OD severity measured using, among other things, fiberoptic endoscopic evaluation of swallowing (FEES) and videofluoroscopy of swallowing (VFS). Therefore, dysphagia-specific QoL questionnaires used alongside these instrumental assessments add value by providing insight into patients' perception of OD, which can be taken into account in the treatment plan. There are dysphagia-specific quality-of-life questionnaires that are actively used today: Swallowing Quality of Life Questionnaire (SWAL-QOL, 44 items), Swallowing Disability Index (30 items), Dysphagia Handicap Index (25 items) and M.D. Anderson Dysphagia Inventory (MDADI, 20 items). Multidisciplinary dysphagia clinics in our country mostly focus on the head and neck. It is visited by patients with OD of oncological or neurological origin.The M. D. Anderson dysphagia inventory is an easier inventory to perform since it has a smaller number of questions and contains more standard questions compared to other currently used questionnaires. Other questionnaires, such as the SWAL-QOL-TR and the Swallowing Disability Index, are longer than the MDADI and take more time to complete. The purpose of this study is M.D. Validity of the Turkish version of the Anderson Dysphagia Inventory for the Turkish population, reliability and cultural adaptation.

• Study Type: Observational
• Enrollment (Estimated): 170

Contacts and Locations

• Study Contact: Name: Muserrefe Nur Keles, PhD; Phone Number: +90 5426622464; Email: muserrefkeles19@gmail.com

Study Locations

• Turkey
  • Ankara, Turkey, 06500
    • Recruiting
    • Gazi University, Faculty of Health and Sciences, Department of Physiotherapy and Rehabilitation Recruiting Ankara, Turkey, 06500
    • Contact: Muserref KELES, PhD; Phone Number: +90 5426622464; Email: muserref-1@hotmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Adults with diagnosed with neurologic disorder and having oropharyngeal dysphagia and healthy adults

Description

Inclusion Criteria:

Group 1:

• Diagnosed with neurologic disorder
• Able to speak, read, understand and write in Turkish
• History of dysphagia during 6 months

Group 2:

• Able to speak, read, understand and write in Turkish
• Healthy adults

Exclusion Criteria:

• Mini Mental State Examination score below 23 points
• History of head and neck cancer (HNC),
• Age below 18 or above 85 years.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
1; Patients who are diagnosed with neurologic disorders The first group consists of 170 diagnosed with neurologic disorders who have at least six months of dysphagia complaints. The participants will given the Turkish version of M.D. Anderson Dysphagia Inventory, consisted of 20 questions, Swallowing Quality-of-Life Questionnaire and Mini Mental Questionnaire. After the two weeks, 50 participants will given the MDADI for sampling.	Other: Turkish Version of M. D. Anderson Dysphagia Inventory; Turkish Validation and Cultural Adaptation of M. D. Anderson Dysphagia Inventory in Neurologic Patients
2; Healthy subjects The second group consists of 50 healty participants will given the MDADI consists of 20 questions and Swallowing Quality-of-Life Questionnaire.	Other: Turkish Version of M. D. Anderson Dysphagia Inventory; Turkish Validation and Cultural Adaptation of M. D. Anderson Dysphagia Inventory in Neurologic Patients

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Turkish Version of M. D. Anderson Dysphagia Inventory	The M.D Anderson Dysphagia Inventory is a self-administered, psychometrically validated dysphagia-specific questionnaire for cancer patients that is designed to assess the impact of dysphagia on health-related quality of life . Like the original English version, the validated Turkish translation of the M.D. Anderson Dysphagia Inventory consists of 20 items pooled in 4 subscales: the global scale (1 item); the functional scale (5 items); the physical scale (8 items); and the emotional scale (6 items)The global question was scored individually, and the mean score of each subscale (emotional, physical, and functional) was multiplied by 20 to obtain a total score with a range from zero (extremely low functioning) to 100 (high functioning). A higher M. D. Anderson Dysphagia Inventory score is indicative of better day-to-day functioning and quality of life.	Baseline
Turkish Version of M. D. Anderson Dysphagia Inventory	The M.D Anderson Dysphagia Inventory is a self-administered, psychometrically validated dysphagia-specific questionnaire for cancer patients that is designed to assess the impact of dysphagia on health-related quality of life . Like the original English version, the validated Turkish translation of the M.D. Anderson Dysphagia Inventory consists of 20 items pooled in 4 subscales: the global scale (1 item); the functional scale (5 items); the physical scale (8 items); and the emotional scale (6 items)The global question was scored individually, and the mean score of each subscale (emotional, physical, and functional) was multiplied by 20 to obtain a total score with a range from zero (extremely low functioning) to 100 (high functioning). A higher M. D. Anderson Dysphagia Inventory score is indicative of better day-to-day functioning and quality of life.	Two weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The Swallowing Quality-of-Life Questionnaire	The Swallowing Quality-of-Life Questionnaire was designed to evaluate the impact of dysphagia on health-related quality of life in dysphagic patients. It consists of 44 items divided among 11 domains: general burden (2 items); food selection (2 items); eating duration (2 items); eating desire (3 items); fear of eating (4 items); sleep (2 items); fatigue (3 items); communication (2 items); mental health (5 items); social functioning (5 items); and frequency of symptoms (14 items). Each item is scored on a 5-point scale: the higher the score, the better the swallow-related quality of life. Completion of the questionnaire takes 15-30 min. The Turkish version of the Swallowing Quality of Life is considered the gold standard for determining dysphagia specific quality of life in patients with dysphagia.	Baseline

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Subject Demographics and Medical History	The median values of age and ratio of gender in all groups. Medical Diagnoses.	Baseline

Collaborators and Investigators

• Sponsor: Gazi University
• Investigators: Study Chair: Muserrefe Nur Keles, PhD, Gazi University

Study record dates

Study Major Dates

• Study Start (Actual): December 19, 2023
• Primary Completion (Estimated): February 19, 2024
• Study Completion (Estimated): May 19, 2024

Study Registration Dates

• First Submitted: December 17, 2023
• First Submitted That Met QC Criteria: January 8, 2024
• First Posted (Actual): January 9, 2024

Study Record Updates

• Last Update Posted (Actual): January 9, 2024
• Last Update Submitted That Met QC Criteria: January 8, 2024
• Last Verified: January 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Digestive System Diseases; Gastrointestinal Diseases; Pharyngeal Diseases; Otorhinolaryngologic Diseases; Esophageal Diseases; Nervous System Diseases; Deglutition Disorders
• Other Study ID Numbers: 187765

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No