Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong

January 14, 2024 updated by: Jane Yidan Zhu

A Retrospective Review on Charlson Comorbidity Index (CCI) as a Predictor of Return-of-spontaneous-circulation and Survival-to-discharge of Geriatric In-hospital Cardiopulmonary Resuscitation (CPR) in a Regional Acute Hospital in Hong Kong

The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:

  • Whether age would affect outcome
  • Whether Charlson Comorbidity Index would affect outcome
  • Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival.

Researchers would compare the patients who deceased with the patients who survived.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The goal of this review was to investigate the impact of age, existing medical conditions. and other factors before cardiac arrest in predicting outcome of in-hospital cardiopulmonary resuscitation (CPR) of older persons.

It was conducted on all patients aged ≥ 65, who underwent CPR in acute medical and geriatric wards (excluding Intensive Care Unit) in United Christian Hospital from January 2017 to December 2018.

Study Type

Observational

Enrollment (Actual)

394

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Hong Kong
      • Hong Kong, Hong Kong, China
        • Haven of Hope Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (a regional acute hospital with total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018

Description

Inclusion Criteria:

  • All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
  • In patients with multiple resuscitation events, only the first in-hospital CPR was included.

Exclusion Criteria:

  • Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
  • Patients younger than 65 years old
  • Out-of-hospital CPR in the index admission
  • CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.
Time Frame: 2017 - 2018
Sustained ROSC is defined as documented return of adequate circulation in the absence of ongoing chest compressions, and the duration should be of 20 minutes or above
2017 - 2018

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Jane Yidan Zhu

Investigators

  • Principal Investigator: JANE YIDAN ZHU, Haven of Hope Hospital, Hong Kong

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 2, 2019

Primary Completion (Actual)

December 31, 2019

Study Completion (Actual)

December 31, 2019

Study Registration Dates

First Submitted

October 1, 2023

First Submitted That Met QC Criteria

January 14, 2024

First Posted (Actual)

January 18, 2024

Study Record Updates

Last Update Posted (Actual)

January 18, 2024

Last Update Submitted That Met QC Criteria

January 14, 2024

Last Verified

January 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • CCI and outcome of CPR

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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