Effect of Exercise on Smokers

Acute Effects of High Intensity Aerobic Exercise on Respiratory Function and Cognitive Status in Smoker Healthcare Workers

When we look at the literature, although 202 results are found when "high intensity training" AND "aerobic" is written in the PUBMED database, 27 to 86 results are found when "high intensity training" AND "cognitive" and "high intensity training" AND "respiratory" are written and searched. 5 results are found when "high intensity training" AND "smoking" is searched, but there is no study investigating cognitive and respiratory functions, and no results are found when "high intensity training" AND "smoker" is searched. As far as is known, there is no study investigating the acute effect of high intensity aerobic exercise on respiratory functions and cognitive status in special education personnel who smoke. We aim to contribute to the literature with this original aspect of our study.

Study Overview

• Status: Completed
• Conditions: Smokers
• Intervention / Treatment: Other: High Intensity Exercise + Placebo; Other: Low Intensity Exercise + Placebo

Detailed Description

Primary objective: The primary objective of the study is to investigate the acute effects of high-intensity aerobic exercise on respiratory functions in special education personnel who smoke.

Secondary objective: The secondary objective of the study is to investigate the acute effects of high-intensity aerobic exercise on cognitive status in special education personnel who smoke.

Study questions

• Is there an acute effect of high-intensity aerobic exercise on respiratory functions in special education personnel who smoke?
• Is there an acute effect of high-intensity aerobic exercise on cognitive status in special education personnel who smoke?

Study Hypotheses:

H0: There is no acute effect of high-intensity aerobic exercise on respiratory functions in special education personnel who smoke.

H1: There is an acute effect of high-intensity aerobic exercise on respiratory functions in special education personnel who smoke.

H2: There is no acute effect of high-intensity aerobic exercise on cognitive status in special education personnel who smoke.

H3: High-intensity aerobic exercise has an acute effect on cognitive status in special education personnel who smoke.

H4: High-intensity aerobic exercise has a greater acute effect on respiratory function and cognitive status in special education personnel who smoke than low-intensity training.

H5: High-intensity aerobic exercise has a less acute effect on respiratory function and cognitive status in special education personnel who smoke than low-intensity training.

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey
    • Istanbul Gedik University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Volunteering to participate in the study
• Participating in the Fageström Nicotine Dependence Questionnaire
• No comorbidities
• No comorbid diseases related to the orthopedic, neurological, cardiopulmonary system
• Participants who have not participated in another clinical trial in the last month

Exclusion Criteria:

• Participants who have had orthopedic and cardiopulmonary surgery in the last year
• Those with cardiac or pulmonary system disease
• Having sensory loss
• Participants with leg length inequality

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: high-intensity aerobic exercise group	Other: High Intensity Exercise + Placebo; high intensity exercise
Active Comparator: low-intensity aerobic exercise group	Other: Low Intensity Exercise + Placebo; low intensity exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
FVC Measurement	Respiratory Function Test. The COSMED microQuark spirometer used. Lung volume was evaluated.	Duration of change in 1 day.
FEV1 Measurement	Respiratory Function Test. The COSMED microQuark spirometer used. Lung volume was evaluated.	Duration of change in 1 day.
Smoking dependence level measurement	Meausered with Fagerström Nicotine Dependence Questionnaire (FNBA)	Duration of change in 1 day.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Cognitive status measurement with MOCA	Measured with Montreal Cognitive Function Assessment Scale (MOCA)	Duration of change in 1 day.
Cognitive status measurement with Stroop Test	Measured with Stroop Test	Duration of change in 1 day.

Collaborators and Investigators

• Sponsor: Istanbul Medipol University Hospital
• Collaborators: Istanbul Gedik University

Study record dates

Study Major Dates

• Study Start (Actual): September 3, 2023
• Primary Completion (Actual): December 3, 2024
• Study Completion (Actual): December 3, 2024

Study Registration Dates

• First Submitted: January 28, 2025
• First Submitted That Met QC Criteria: January 28, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: January 28, 2025
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Keywords: exercise; aerobic; smoker
• Other Study ID Numbers: E56365223-050.02.02.2023.13754

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No