Health Literacy and Osteoporosis Awareness

February 11, 2026 updated by: Nurten NAS KIRDAR, Bandırma Onyedi Eylül University

Health Literacy and Osteoporosis Awareness Levels Among Individuals in the Age Group at Risk for Osteoporosis: A Descriptive Cross-Sectional Study

Osteoporosis (OP) is defined as a progressive metabolic bone disease characterized by low bone mass and deterioration of the microarchitecture of bone tissue, resulting in increased bone fragility and a higher risk of fractures. Osteoporosis and related fractures constitute a significant public health problem in our increasingly aging world. It is currently estimated that more than 200 million people worldwide are affected by osteoporosis. The most important clinical outcome of osteoporosis is fragility fractures that occur as a result of low-energy trauma.

Health literacy is an important determinant of both individual and public health and is considered a fundamental component of patient-centered care. Health literacy is defined as the ability to obtain, process, and understand relevant health information in order to make appropriate health decisions, and limited health literacy is recognized as a global public health problem. Many patients have difficulty understanding their medical conditions, medications, and care instructions due to inadequate health literacy. Patients with limited health literacy often have insufficient understanding of diagnostic and treatment protocols, which poses a risk for potential misuse of healthcare services and poorer health outcomes. Low levels of health literacy are also associated with increased hospital admissions and higher mortality rates. In contrast, higher health literacy is associated with greater health knowledge and self-confidence.

Screening for the prevention of osteoporosis and related fractures can reduce fracture-associated mortality and morbidity. Such screening may be initiated by physicians through the evaluation of osteoporosis risk factors during clinical visits, or in some cases, based on patient demand, again guided by the physician's assessment of risk factors. One of the most important factors influencing patient demand is the level of osteoporosis awareness. Early diagnosis and treatment in at-risk patient groups before fractures occur can help prevent potential complications.

In recent years, numerous scientific studies have investigated levels of osteoporosis knowledge and awareness. Some of these studies have focused on specific populations, such as individuals with spinal cord injury, rheumatoid arthritis, or patients followed after osteoporotic fractures, while others have been conducted exclusively among women.

With increasing life expectancy and the growth of the elderly population, osteoporosis has become a more prominent health issue and is no longer limited to postmenopausal women, but rather represents a serious health problem affecting individuals of both sexes.

The aim of the present study is to assess health literacy and the level of osteoporosis awareness among individuals in the age group at risk for osteoporosis and to identify factors influencing these outcomes. One of the distinguishing features of our study compared to previous research is the inclusion of both sexes. Another distinguishing aspect is the emphasis on the indication for osteoporosis screening in older adults, even in the absence of obvious risk factors such as chronic disease, medication use, or a history of fractures. We hope that our study will contribute to the existing literature on osteoporosis, health literacy, and osteoporosis awareness.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Following approval from the institutional ethics committee, female patients aged 65 years and older and male patients aged 70 years and older who present to our outpatient clinic will be enrolled in the study. The study is designed as a cross-sectional study. All patients who apply to the Physical Medicine and Rehabilitation outpatient clinic and meet the inclusion criteria will be informed about the study, and those who provide written informed consent will be included. Participants' age, sex, and educational level will be recorded.

Health literacy will be assessed using the THLS-32 (Turkish Health Literacy Scale-32). The THLS-32 is a 32-item questionnaire that evaluates two domains (treatment and services; disease prevention/health promotion) and four processes (accessing health-related information, understanding health-related information, appraising health-related information, and applying/using health-related information). The Turkish validity and reliability of the Health Literacy Scale used in European countries were established in 2016, leading to the development of the THLS-32 scale. Each item is rated as very easy (1), easy (2), difficult (3), very difficult (4), or "I do not know" (5). The index score is calculated using the formula "index = (mean - 1) × (50/3)," resulting in a score range of 0-50. Cut-off values are defined as follows: 0-25 "inadequate health literacy," >25-33 "problematic/limited health literacy," >33-42 "adequate health literacy," and >42-50 "excellent health literacy." In this survey, the minimum score is 0 and the maximum score is 50. Higher scores indicate higher health literacy levels.

Osteoporosis awareness will be evaluated using the "Osteoporosis Awareness Scale," which has demonstrated Turkish validity and reliability. The final Turkish version of the Osteoporosis Awareness Scale consists of 27 items and five subscales. The 27 items are rated on a 4-point Likert scale as follows: "I know very well" (4), "I know" (3), "I know a little" (2), and "I do not know at all" (1). The total score ranges from a minimum of 27 to a maximum of 108. Although the scale has no reverse-scored items or cut-off points, higher total scores indicate greater osteoporosis awareness. The subscales include Bone Physiology (items 22-27), Preventive Behaviors (items 4, 5, 7, 8, 9, 10, and 21), Risk Factors (items 11-15), Exercise (items 1, 2, 3, and 6), and Characteristics of Osteoporosis (items 16-20).

The collected data will be analyzed using an appropriate statistical software program.

No tests, laboratory examinations, or interventions will be performed as part of this study.

No specific safety precautions are required during the implementation of the study.

Inclusion Criteria

Female patients aged 65 years and older

Male patients aged 70 years and older

Exclusion Criteria

Cognitive dysfunction

Dementia

Uncontrolled psychiatric disorders

Adjustment disorders

Intellectual disability

Statistical Analysis

The collected data will be analyzed using SPSS version 25.0 (IBM SPSS Statistics 25 software; Armonk, NY: IBM Corp.). Continuous variables will be presented as mean ± standard deviation, and categorical variables as numbers and percentages. When parametric test assumptions are met, comparisons between independent groups will be performed using the independent samples t-test and one-way analysis of variance (ANOVA). When parametric assumptions are not met, the Mann-Whitney U test and Kruskal-Wallis test will be used. Differences between categorical variables will be examined using the chi-square test. Relationships between continuous variables will be analyzed using Spearman or Pearson correlation analyses, appropriate regression models, and differences between categorical variables will be assessed using chi-square analysis. Multivariate regression analysis is planned to evaluate the relationships between variables. A p-value < 0.05 will be considered statistically significant.

At the beginning of the study, the sample size was calculated using the G*Power 3.1.9 software. Based on reference studies, a moderate effect size of d = 0.63 was assumed, and a total sample size of at least 64 participants (32 women and 32 men) was determined.

Study Type

Observational

Enrollment (Estimated)

190

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Turkey (Türkiye)
    • Bandırma
      • Balıkesir, Bandırma, Turkey (Türkiye), 10200
        • Recruiting
        • Bandırma Onyedi Eylul University Faculty of Medicine
        • Contact:
        • Principal Investigator:
          • Nurten Nas Kırdar, Dr. Öğr. Üyesi

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

One of the distinguishing features of our study compared to previous research is the inclusion of both sexes. Another distinguishing aspect is the emphasis on the indication for osteoporosis screening in older adults, even in the absence of obvious risk factors such as chronic disease, medication use, or a history of fractures.

Description

Inclusion Criteria:

  • Female patients aged 65 years and older
  • Male patients aged 70 years and older

Exclusion Criteria:

  • Cognitive dysfunction
  • Dementia
  • Uncontrolled psychiatric disorders
  • Adjustment disorders
  • Intellectual disability

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
95 men and 95 women
equal number of patients of both sexes
Other: Patients will only fill out a questionnaire.
Health literacy will be assessed using the TSOY-32 (Turkish Health Literacy Scale-32). The TSOY-32 is a 32-item questionnaire that evaluates two domains (treatment and services; disease prevention/health promotion) and four processes (accessing health-related information, understanding health-related information, appraising health-related information, and applying/using health-related information). The Turkish validity and reliability of the Health Literacy Scale used in European countries were established in 2016 by Okyay and Abacıgil, leading to the development of the TSOY-32 scale (12). Each item is rated as very easy (1), easy (2), difficult (3), very difficult (4), or "I do not know" (5). The index score is calculated using the formula "index = (mean - 1) × (50/3)," resulting in a score range of 0-50. Cut-off values are defined as follows: 0-25 "inadequate health literacy," >25-33 "problematic/limited health literacy," >33-42 "adequate health literacy," and >42-50 "excellent healt

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
THLS-32 (Turkish Health Literacy Scale-32)
Time Frame: 6 months
THLS-32 (Turkish Health Literacy Scale-32) for health literacy. In this survey, the minimum score is 0 and the maximum score is 50. Higher scores indicate higher health literacy levels.
6 months
Osteoporosis Awareness Scale
Time Frame: 6 months
"Osteoporosis Awareness Scale" for osteoporosis awareness. The total score ranges from a minimum of 27 to a maximum of 108. Although the scale has no reverse-scored items or cut-off points, higher total scores indicate greater osteoporosis awareness.
6 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Relationship between age and THSL-32
Time Frame: 6 months
-Relationship between age and THSL-32
6 months
-Relationship between age and the "Osteoporosis Awareness Scale"
Time Frame: 6 months
-Relationship between age and the "Osteoporosis Awareness Scale"
6 months
-Relationship between gender and THSL-32
Time Frame: 6 months
Relationship between gender and THSL-32
6 months
-Relationship between gender and the "Osteoporosis Awareness Scale"
Time Frame: 6 months
-Relationship between gender and the "Osteoporosis Awareness Scale"
6 months
-Relationship between education level and THSL-32
Time Frame: 6 months
-Relationship between education level and THSL-32
6 months
Relationship between education level and the "Osteoporosis Awareness Scale"
Time Frame: 6 months
Relationship between education level and the "Osteoporosis Awareness Scale"
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bandırma Onyedi Eylül University

Investigators

  • Principal Investigator: Nurten Nas Kırdar, Dr. Öğr. Üyesi, Bandırma Onyedi Eylül University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 9, 2025

Primary Completion (Estimated)

March 1, 2026

Study Completion (Estimated)

March 30, 2026

Study Registration Dates

First Submitted

January 24, 2026

First Submitted That Met QC Criteria

February 11, 2026

First Posted (Actual)

February 19, 2026

Study Record Updates

Last Update Posted (Actual)

February 19, 2026

Last Update Submitted That Met QC Criteria

February 11, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • E-67961857-050.04-2500024943

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

The data analysis and results of our scientific research have not yet been completed. The final version of our study will be shared with readers by being published in an academic journal in the field of medicine. If a suitable journal deems our study suitable for publication after the peer review process, other researchers will be able to read and benefit from this publication once it is released.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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