Using Telemedicine to Assist in the Clinical Care of Patients With Decompensated Cirrhosis

February 23, 2026 updated by: National Taiwan University Hospital

The goal of this clinical trial is to learn if an integrated digital and telemedicine care model works to manage decompensated cirrhosis in patients. It will also learn about the impact of this model on healthcare resource consumption and patient quality of life. The main questions it aims to answer are:

  1. Does this telemedicine model lower the number of cirrhosis-related hospitalizations and emergency department visits?
  2. Does the model reduce medical expenses and improve disease outcomes compared to standard care?

Researchers will compare the digital telemedicine care model (utilizing the NTUH-TPC platform and wearable devices) to standard health care to see if the digital approach effectively reduces hospital admissions and medical costs.

Participants will:

  1. Use the NTUH telehealth platform (NTUH-TPC) to access records and upload physiological, medical, and imaging data.
  2. Wear a smart watch for remote physiological monitoring. Receive continuous remote care and proactive follow-ups from case managers.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

120

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Taiwan
      • Taipei, Taiwan, 100
        • National Taiwan University Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Patients with decompensated cirrhosis and a Child score of B or C
  2. Age: 18 years or older
  3. Must return for a follow-up visit at least every 3 months

Exclusion Criteria:

  1. Patients with active malignant tumors (those with a history of malignant tumors must have been cured for at least 2 years)
  2. Patients with an expected survival of less than one year

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Telemedicine care
Telemedice care platform
Device: Telemedicine care
  1. NTUH telehealth platform for cirrhosis, NTUH-TPC
  2. Provide a wearable device (Asus vivowatch 6 aero)
  3. Telemonitoring by case manager
  4. Self-reported information from enrolled patients
No Intervention: Starndard Helath Care
Standard health care

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Liver Disease Severity Scores
Time Frame: 12 months
MELD 3.0 score
12 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Rate of All-Cause Unplanned Hospitalizations
Time Frame: 12 months
It measures how frequently participants are admitted to the hospital for any unexpected medical reason over a 12-month period.
12 months
Rate of All-Cause Unplanned Emergency Room Visits
Time Frame: 12 months
The study tracks every instance a participant visits the Emergency Room (ER) for an unscheduled medical issue over a 12-month period.
12 months
Days alive and out of hospital
Time Frame: 12 months
This metric is a patient-centered outcome used to measure the total amount of time a participant spends healthy and at home, rather than in a hospital or losing life due to disease.
12 months
Quality of Life Score & Patient Satisfaction
Time Frame: 12 months
This composite metric measures how the clinical trial's care models affect the daily well-being, emotional state, and overall happiness of patients living with advanced liver disease. By using thise two questionnaries "CLDQ" and "EQ-5D-5L".
12 months
Feasibility and Adherence to telemedicine
Time Frame: 12 months
Percentage of days with successful vital sign uploads (smartwatch) and response rate to case manager calls
12 months
Total medical expenses at NTUH related to cirrhosis
Time Frame: 12 months
This metric tracks the overall financial cost of healthcare provided specifically for liver disease throughout the study period. (Outpatient + ER + Inpatient)
12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Collaborators

National Science and Technology Council, Taiwan

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

February 23, 2026

Primary Completion (Estimated)

December 31, 2028

Study Completion (Estimated)

December 31, 2028

Study Registration Dates

First Submitted

February 1, 2026

First Submitted That Met QC Criteria

February 23, 2026

First Posted (Actual)

February 27, 2026

Study Record Updates

Last Update Posted (Actual)

February 27, 2026

Last Update Submitted That Met QC Criteria

February 23, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 202410060RINC

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

To protect the patients' privacy information.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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