Clinical Assessment of CAD/CAM Fabricated Lithium-Disilicate Overlay Versus Lithium-disilicate Endocrowns for Restoration of Endodontically Treated Teeth.

March 31, 2026 updated by: Moataz Abd ElHalem, Cairo University

Clinical Assessment of CAD/CAM Fabricated Lithium-Disilicate Overlay Versus Lithium-disilicate Endocrowns for Restoration of Endodontically Treated Teeth. A Randomized Controlled Clinical Study

A Randomized Controlled Clinical Study aims for Clinical Assessment of CAD/CAM Fabricated Lithium-Disilicate overlay in comparison to Lithium-disilicate Endocrowns for Restoration of Endodontically Treated Teeth.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Investigators are going to compare the clinical behavior of the lithium disilicate overlay as a more conservative line of treatment for endodontic treated teeth. overlays will be compared to the lithium disilicate endocrowns .primary outcome will be marginal adaptation ,secondary outcomes will be survival and patient satisfaction . Baseline, 5, 10, 15, and 20 months follow up will extend to 20 months(Baseline, 5, 10, 15, and 20 months) .This is a randomized, controlled, parallel-group clinical trial with 1:1 allocation ratio.

Study Type

Interventional

Enrollment (Actual)

25

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt, 12567
        • Faculty of Dentistry Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Patients with endodontically treated teeth indicated to ceramic Endocrowns.
  • Patients with endodontically treated teeth indicated to ceramic overlays.
  • Physically and psychologically able to tolerate conventional restorative procedures.
  • Have no active periodontal or periapical diseases.
  • Maintenance of good oral hygiene.
  • Willing to return for follow-up examinations and evaluation.

Exclusion Criteria:

  • Patients in the growth stage with partially erupted teeth.
  • Patients with para-functional habits.
  • Patients with defective endodontic treatment.
  • Patients with poor oral hygiene and motivation.
  • Psychiatric problems or unrealistic expectations.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: lithium disilicate endocrown
Other: lithium disilicate overlays
indirect partial coverage restoration that cover mainly the occlusal surface of posterior teeth
Other Names:
  • occlusal veneer ,ceramic partial coverage
Active Comparator: overlay
Other: lithium disilicate overlays
indirect partial coverage restoration that cover mainly the occlusal surface of posterior teeth
Other Names:
  • occlusal veneer ,ceramic partial coverage

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
marginal adaptations
Time Frame: Baseline, 5 months, 10 months, 15 months, and 20 months
Marginal adaptation will be evaluated using Modified United States Public Health Service (USPHS) criteria by two calibrated independent examiners. Scores will be recorded as Alpha, Bravo, or Charlie based on marginal integrity.
Baseline, 5 months, 10 months, 15 months, and 20 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
marginal discoloration
Time Frame: Baseline, 5, 10, 15, and 20 months
change in margins colour as a result of leakage , Assessed using Modified USPHS criteria as Alpha, Bravo, or Charlie scores.
Baseline, 5, 10, 15, and 20 months
patient satisfaction
Time Frame: 20 months
patient acceptance to the treatment
20 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Collaborators

Ahram Canadian University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2023

Primary Completion (Actual)

March 1, 2024

Study Completion (Actual)

March 15, 2024

Study Registration Dates

First Submitted

March 9, 2026

First Submitted That Met QC Criteria

March 31, 2026

First Posted (Actual)

April 2, 2026

Study Record Updates

Last Update Posted (Actual)

April 2, 2026

Last Update Submitted That Met QC Criteria

March 31, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Theme 3,Objective FPD 3-2-2

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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