Bilateral Erector Spinae Plane Block Versus Bilateral Quadratus Lumborum Plane Block for Postoperative Anaelgesia After Lumbar Spine Surgery

April 2, 2026 updated by: Ain Shams University
The aim of this study is to compare postoperative analgesia and duration for each block performance plus complications after surgery in lumbar spine fixation.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

40

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt, 11511
        • AinShamsU

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Aged between 18 and 65 years.
  • American Society of Anesthesiologists (ASA) physical status I to II.
  • Body mass index (BMI) less than 35 kg/m2.

Exclusion Criteria:

  • Revision surgery.
  • More than three levels surgery.
  • Abnormal state of blood coagulation.
  • Chronic opioid consumption.
  • Local infection at the injection site).
  • Allergy to any involved medications.
  • Taking opioids within the past two weeks prior to surgery.
  • Time of surgery more than 4 hours.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Ultrasound-guided quadratus lumborum block
Procedure: Ultrasound-guided quadratus lumborum block (QLB)
And ultrasound guided QLB block with transmuscular approach was performed using 0.5 ml/kg 0.25% bupivacaine to the patients in QLB group
Active Comparator: Ultrasound Guided Erector Spinae Plane Block (ESPB)
Procedure: Ultrasound-guided quadratus lumborum block (QLB)
And ultrasound guided QLB block with transmuscular approach was performed using 0.5 ml/kg 0.25% bupivacaine to the patients in QLB group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Comparison between postoperative analgesia of QLB and ESPB after lumbar spine surgery via VAS score measurement
Time Frame: VAS Score will be used to assess pain or discomfort in postoperative at 2, 4, 6, 12, 24 hours
The Visual Analog Scale (VAS) is used to assess pain intensity. It consists of a 10 cm line where 0 indicates "no pain" and 10 indicates "the worst possible pain." Higher scores indicate greater pain intensity.
VAS Score will be used to assess pain or discomfort in postoperative at 2, 4, 6, 12, 24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ain Shams University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

  • Fakhry, Mahmoud, D., ElMoutaz Mahmoud, H., Yehia Kassim, D. & NegmEldeen AbdElAzeem, H. 2024. Erector spinae plane block versus quadratus lumborum block for postoperative analgesia after laparoscopic resection of colorectal cancer: A prospective randomized study. Anesthesiol Res Pract, 20, 10.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2025

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

July 1, 2026

Study Registration Dates

First Submitted

April 2, 2026

First Submitted That Met QC Criteria

April 2, 2026

First Posted (Actual)

April 8, 2026

Study Record Updates

Last Update Posted (Actual)

April 8, 2026

Last Update Submitted That Met QC Criteria

April 2, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • MMASU 15/2024

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

To maintain participant confidentiality and because there is no established institutional repository for sharing raw individual participant data for this specific project.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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