Immediate Implant Placement Using Socket Shield With CGF (CGF)

April 8, 2026 updated by: Areej khalid rashyd, Cairo University

Clinical and Radiographic Evaluation of Concentrated Growth Factors With Simultaneous Immediate Implant Placement in Socket Shield Technique

This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Outcomes will include crestal bone level changes assessed by CBCT and implant stability measured using Osstell.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

This prospective case series study will be conducted to evaluate clinically and radiographically the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) during immediate implant placement in the esthetic zone.

Eligible patients requiring extraction and immediate implant placement in the maxillary anterior or premolar region will be included. Following atraumatic extraction, partial extraction therapy using the socket shield technique will be performed, leaving the buccal root fragment in place. Implant osteotomy and placement will then be carried out according to manufacturer instructions.

Autologous concentrated growth factors will be prepared from the patient's blood using a CGF centrifugation protocol. The CGF gel will be packed into the jumping gap between the implant and socket wall to promote bone regeneration and healing.

Clinical and radiographic evaluation will be performed using CBCT at baseline, 2 weeks, and 6 months postoperatively. The primary outcome will be crestal bone level changes measured radiographically, while the secondary outcome will include implant stability assessed using Osstell measurements (ISQ values).

Seven participants will be recruited in this case series. Follow-up will be conducted to evaluate healing, bone remodeling, and implant stability.

Study Type

Interventional

Enrollment (Estimated)

7

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt, 11765
        • Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age ≥18 years old. (Younis, W., & El-Rashidy, A. 2020).
  • Both male and female patients.
  • Maxillary, anterior and premolar segment.

Exclusion Criteria:

  • A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).
  • Presence of active or untreated periodontal disease.
  • Vertical root fractures involving the buccal aspect.
  • Tooth /teeth with horizontal fractures below bone level.
  • Tooth /teeth with external or internal resorption.
  • Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Socket Shield Technique with CGF
Immediate implant placement using socket shield technique combined with concentrated growth factors in the esthetic zone.
Procedure: Immediate implant placement with Socket Shield Technique and CGF
Partial extraction therapy using the socket shield technique followed by immediate implant placement. Concentrated growth factors prepared from autologous blood will be packed in the jumping gap to enhance bone regeneration and healing.
Other Names:
  • Immediate implant placement
  • Socket Shield technique
  • Concentrated Growth Factors

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Crestal bone level
Time Frame: 2 weeks and 6 months post-operatively
Radiographic evaluation of crestal bone level changes around the implant using CBCT, measured in millimeters (mm).
2 weeks and 6 months post-operatively

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Implant stability
Time Frame: Immediately after implant placement and at 6 months
Implant stability will be assessed using resonance frequency analysis with the Osstell device and recorded as Implant Stability Quotient (ISQ). ISQ values range from 1 to 100, where higher values indicate greater implant stability and a better outcome.
Immediately after implant placement and at 6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Study Director: Abdelmoez Mohamed El-Sharkawy, Associate Professor, Cairo University
  • Study Chair: Tarek I.A El-Ghareeb, PHD Holder, Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 1, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

December 30, 2026

Study Registration Dates

First Submitted

April 3, 2026

First Submitted That Met QC Criteria

April 3, 2026

First Posted (Actual)

April 9, 2026

Study Record Updates

Last Update Posted (Actual)

April 13, 2026

Last Update Submitted That Met QC Criteria

April 8, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • omfs_ 3-3-20

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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