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Hydration and Exercise Performance in Cycling

11. oktober 2018 opdateret af: University of Exeter

How Does Altering the Composition of Ingested Fluids Affect Hydration Status Whilst Cycling?

This study will evaluate the effects manipulating ingested fluids can have on hydration status and cycling performance. There will be 4 different conditions.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Being dehydrated can decrease endurance exercise performance. The investigators wish to test which of three drinks is most effective at re-hydrating cyclists and if this affects performance. Subjects will undertake 4 tests: once dehydrated, once hydrated with water, once hydrated with a sports-specific drink, and once with an altered sports drink. Blood samples will be taken and expired gasses will be sampled at various time points throughout the tests for later analysis. A small amount of labelled water will be consumed with each drink, a technique which will allow us to quantify the absorption of each of the drinks.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

15

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Det Forenede Kongerige
    • Devon
      • Exeter, Devon, Det Forenede Kongerige, EX1 2LU
        • School of Sports and Health Sciences

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år til 50 år (Voksen)

Tager imod sunde frivillige

Ja

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inclusion Criteria:

  • Highly trained cyclists (vo2max >55 ml/kg/min, PPO (peak power output) > 4 w/kg)
  • Training at least 4 times a week
  • Females must be taking an oral contraceptive, or using the contraceptive implant

Exclusion Criteria:

  • Recent history of musculoskeletal injury
  • Diagnosed cardiovascular disease
  • Regular use of nutritional supplements that may interfere with the protocol

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Crossover opgave
  • Maskning: Dobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Dehydrated
90 minutes cycling, without the ingestion of any fluids, followed by a 15 minute cycling time trial test
Andet: Dehydrated
N/A: see arm description
Eksperimentel: Hypotonic
90 minutes cycling, with the ingestion of six 250 ml carbohydrate (6g sucrose, 3g glucose) drinks, followed by a 15 minute cycling time trial test
Kosttilskud: Hypotonic
N/A: see arm description
Eksperimentel: Isotonic
90 minutes cycling, with the ingestion of six 250 ml carbohydrate (6g glucose, 3g fructose) drinks, followed by a 15 minute cycling time trial test
Kosttilskud: Isotonic
N/A: see arm description
Eksperimentel: Placebo
90 minutes cycling, with the ingestion of six 250 ml taste-matched water drinks, followed by a 15 minute cycling time trial test
Kosttilskud: Placebo
N/A: se armbeskrivelse

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Absorption of fluid through the gut
Tidsramme: To begin 10 minutes after the completion of the 90 minute steady-state cycle
Absorption of drinks through the gut will be measured using 2 boluses of deuterated water. This will be consumed alongside 2 of the drinks, and blood samples will be used to quantify enrichment. Total body water calculations are required to provide corrections in equations related to D2O. H218O will be consumed in order to quantify total body water: this will be provided in a single bolus before each trial.
To begin 10 minutes after the completion of the 90 minute steady-state cycle

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Work done (kJ) during 15 minute cycling time-trial
Tidsramme: Throughout the 90 minute steady-state cycle & the 15 minute time trial.
Subjects will perform a cycle ergometer protocol that has been shown to be reproducible in athletes. Subjects will complete the time trial on a Lode Excalibur cycling ergometer. Software linked to this software will record work done and power output.
Throughout the 90 minute steady-state cycle & the 15 minute time trial.

Andre resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Substrate utilisation
Tidsramme: Throughout the 90 minute steady-state cycle
Substrate utilisation will be calculated from data collected through a metabolic cart and its software. It will be measured during the 90-minute steady-state cycle for 4 periods of 3 minutes. Carbohydrate and lipid oxidation rates will be calculated using equations by Jeukendrup & Wallis (2005).
Throughout the 90 minute steady-state cycle
Plasma metabolites
Tidsramme: Throughout the 90 minute steady-state cycle and time-trial
A cannula will be used to draw blood from subjects at several time points. Whole blood samples will be analysed immediately for plasma glucose, plasma lactate, haemoglobin content, haematocrit and plasma volume. Remaining whole blood will be centrifuged immediately and its plasma split into aliquots and stored in a -20°C freezer. At the end of the trial, plasma samples will be moved to a -80°C freezer for later analysis for sodium, glycerol, and NEFA.
Throughout the 90 minute steady-state cycle and time-trial
Heart rate
Tidsramme: Throughout the 90 minute steady-state cycle and time-trial
Heart rate will be measured throughout with the use of a heart rate monitor.
Throughout the 90 minute steady-state cycle and time-trial
RPE (rating of perceived exertion)
Tidsramme: Throughout the 90 minute steady-state cycle and time-trial
RPE will be measured using the Borg Scale.
Throughout the 90 minute steady-state cycle and time-trial
Core body temperature
Tidsramme: Throughout the 90 minute steady-state cycle and time-trial
Core temperature will be measured throughout with the use of an ingestible core-body temperature pill (HQ Inc, FL, USA).
Throughout the 90 minute steady-state cycle and time-trial

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

University of Exeter

Efterforskere

  • Ledende efterforsker: Andrew D Davenport, MSc, The University of Exeter

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

11. september 2017

Primær færdiggørelse (Faktiske)

1. juni 2018

Studieafslutning (Faktiske)

1. juni 2018

Datoer for studieregistrering

Først indsendt

13. september 2017

Først indsendt, der opfyldte QC-kriterier

2. oktober 2017

Først opslået (Faktiske)

6. oktober 2017

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

12. oktober 2018

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

11. oktober 2018

Sidst verificeret

1. oktober 2018

Mere information

Begreber relateret til denne undersøgelse

Andre undersøgelses-id-numre

  • 170614/A/01

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

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Kosttilskud

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Placeringer

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