Syndrome and Aspiration Pneumonia in Intensive Care (SPIRE)

Inclusion Criteria:

• Altered consciousness defined by a Glasgow Coma Scale score less than or equal to 8 before protection of the upper airway by endotracheal intubation
• Patient under mechanical ventilation

Exclusion Criteria:

• Patient with pre-existing impairment of laryngeal function in Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, laryngeal cancer, radiotherapy laryngeal
• Patient under guardianship
• Inpatient without consent
• Pregnant woman
• Patient previously treated with antibiotics for more than 24 hours at the time of ICU admission
• Patient with infection at ICU admission which justified probabilist antibiotic treatment
• Lack of social security
• Refusal of the patient or their next of kind