颈椎手法的镇痛作用
2020年7月11日 更新者:Jonathan Daniel Telles、Universidade Federal de Sao Carlos
特定与非特定宫颈手法对健康受试者的镇痛作用
本研究评估了整体和特定颈椎关节操作对健康个体的镇痛作用。
起初,参与者接受了一种干预措施,48 小时后,接受了另一种干预措施。
研究概览
详细说明
颈椎关节手法 (CJM) 通常用于疼痛治疗。
关节操作通过激活位于关节囊或肌肉中的本体感受器,在中枢神经系统内产生一系列刺激,刺激 PAG,通过激活非阿片类药物下行抑制通路引起疼痛抑制。
研究类型
介入性
注册 (实际的)
21
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习地点
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São Paulo
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São Carlos、São Paulo、巴西、13565-905
- Ufscar - Universidade Federal de São Carlos
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参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 至 30年 (成人)
接受健康志愿者
是的
有资格学习的性别
全部
描述
纳入标准:
- 男女健康受试者
- 在过去 90 天内没有疼痛投诉
排除标准:
- 以前的脊柱手术
- 椎管狭窄
- 椎骨骨折
- 脊椎滑脱
- 癌症
- 急性感染
- 出血性疾病
- 活动性肺结核
- 深静脉血栓形成
- 骨质疏松症
- 风湿性疾病
- 代谢性疾病
- 心肺疾病
- 吸烟伤害
- 肌肉骨骼损伤
- 使用起搏器
- 月经期的女性
- 孕妇
- 在过去 48 小时内使用止痛药
- 最近 48 小时内使用过消炎药
- 以前的关节操纵治疗
- 厌恶颈椎关节操作
- 椎动脉试验阳性
- 最近7天头痛
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
- 主要用途:基础科学
- 分配:随机化
- 介入模型:交叉作业
- 屏蔽:双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
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有源比较器:全球操纵
以非特异性方式在颈部区域进行手法治疗。
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治疗师将自己放在担架的头部,用一只手支撑参与者的脸侧。
另一手支撑其对侧面,向对侧旋转颈椎,轻微牵拉组织屏障,进行高速、小幅度旋转的手法冲动。
该程序是双边进行的。
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实验性的:具体操作
专门针对 C6-7 节段进行的手法治疗
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治疗师将自己放在担架的头部,用一只手将第二根手指的中指骨横向放在 C6-7 椎骨的关节突上。
他用对侧手支撑参与者的相对面,倾斜至 C6-7 节段并向对侧旋转至组织屏障,以快速而短时间地执行脉冲。
该程序是双边进行的。
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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前臂后部压痛阈值
大体时间:干预结束后1分钟。
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受试者仰卧在担架上,肘部完全伸展,前臂前部靠在担架上。
受试者被指示在尝试过程中闭上眼睛。
检查者在肘部外上髁下方 10 厘米处的前臂后部区域向无名指方向使用 Somedic II 型数字压力痛计(Somedic Inc, Hörby, Sweden),保持前臂旋前。
然后使用覆盖有 1mm 橡胶的 1cm2 扁平圆形探针以 40kPa/s 的速率垂直于皮肤施加压力,以防止尖锐金属边缘引起的任何皮肤疼痛。
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干预结束后1分钟。
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员:Richard E Liebano, Dr.、Universidade Federal de São Carlos - UFScar
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
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研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2018年6月20日
初级完成 (实际的)
2018年6月20日
研究完成 (实际的)
2018年7月20日
研究注册日期
首次提交
2018年5月17日
首先提交符合 QC 标准的
2018年5月17日
首次发布 (实际的)
2018年5月30日
研究记录更新
最后更新发布 (实际的)
2020年7月14日
上次提交的符合 QC 标准的更新
2020年7月11日
最后验证
2020年7月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
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