Glucose, Whey Protein and Time to the Next Meal on Mealtime Food Intake in Children

The Effect of Glucose, Whey Protein and Time to the Next Meal on Food Intake and Subjective Appetite in Normal Weight and Overweight/Obese Children

The investigators hypothesize that glucose and whey protein given 30 and 60 min before a pizza meal will exert different effects on food intake in adolescent children, and will depend on pubertal stage. Food intake will be measured at 30 and 60 min following a glucose(0.75 g of glucose/kg body weight), whey protein (0.75 g of glucose/kg body weight) or sweetened noncaloric beverage. Subjective appetite will be measured as well.

Study Overview

• Status: Completed
• Conditions: Obesity
• Intervention / Treatment: Dietary supplement: water with noncaloric sweetener; Dietary supplement: water with glucose; Dietary supplement: water and whey protein

• Study Type: Interventional
• Enrollment (Actual): 36
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Canada
  • Ontario
    • Toronto, Ontario, Canada, M5S 3E2
      • Department of Nutritional Sciences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 9 years to 14 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• children with no emotional, behavioral or learning problems

Exclusion Criteria:

• underweight children
• children with emotional, behavioral or learning problems
• children who dislike foods in study

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Single

Number of Arms

6

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: noncaloric beverage; noncaloric sweetened beverage administered 30 min prior to mealtime	Dietary supplement: water with noncaloric sweetener; 0.15 g of sucralose added to water
Experimental: noncaloric beverage (60 min); noncaloric sweetened beverage administered 60 min prior to mealtime	Dietary supplement: water with noncaloric sweetener; 0.15 g of sucralose added to water
Experimental: glucose beverage; glucose beverage administered 30 min prior to mealtime	Dietary supplement: water with glucose; 0.75 g/kg body weight of glucose added to water
Experimental: glucose beverage (60 min); glucose beverage administered 60 min prior to mealtime	Dietary supplement: water with glucose; 0.75 g/kg body weight of glucose added to water
Experimental: whey protein beverage; whey protein beverage administered 30 min prior to mealtime	Dietary supplement: water and whey protein; 0.75 g/kg body weight of whey protein added to water
Experimental: whey protein beverage (60 min); whey protein beverage administered 60 min prior to mealtime	Dietary supplement: water and whey protein; 0.75 g/kg body weight of whey protein added to water

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Food intake (kcal)	30 and 60 min after the treatment

Secondary Outcome Measures

Outcome Measure	Time Frame
subjective appetite	0-120 min

Collaborators and Investigators

• Sponsor: University of Toronto
• Collaborators: Canadian Institutes of Health Research (CIHR)
• Investigators: Principal Investigator: Harvey Anderson, PhD, University of Toronto

Study record dates

Study Major Dates

• Study Start: January 1, 2010
• Primary Completion (Actual): December 1, 2012
• Study Completion (Actual): February 1, 2013

Study Registration Dates

• First Submitted: January 6, 2011
• First Submitted That Met QC Criteria: January 6, 2011
• First Posted (Estimate): January 7, 2011

Study Record Updates

• Last Update Posted (Estimate): February 15, 2013
• Last Update Submitted That Met QC Criteria: February 13, 2013
• Last Verified: February 1, 2013

More Information

Terms related to this study

• Other Study ID Numbers: FoodIntakeKids_21595