- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01598974
Back Pain Response to Different Acupuncture Methods (LBP)
November 27, 2017 updated by: Robert Edwards, Brigham and Women's Hospital
Brain Plasticity Underlying Back Pain Response to Different Acupuncture Methods
Acupuncture has been used for many years to help relieve pain.
However, it is not clear how acupuncture works.
We are doing this study to learn about the effects of different forms of acupuncture on chronic low back pain.
We are interested in learning about brain activity during pain.
We plan to look at brain activity at the beginning and the end of the study, after 6 sessions of acupuncture.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
151
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Massachusetts
-
Charlestown, Massachusetts, United States, 02129
- MGH - Martinos Center
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 60 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Volunteers 18-60 years of age.
- Meet the Classification Criteria of the chronic LBP (having low back pain for more than 6 months), as determined by the referring physician.
- At least 4/10 clinical pain on the 11-point LBP intensity scale.
- Patients must be able to provoke or exacerbate their chronic LBP using our calibrated exercise-like maneuver.
- Must have had a prior evaluation of their low back pain by a health care provider, which may have included radiographic studies. Documentation of this evaluation will be sought from Partners or outside medical records and kept in the subject's research record.
- At least a 10th grade English-reading level; English can be a second language provided that the patients feel they understand all the questions used in the assessment measures.
Exclusion Criteria:
- Specific causes of back pain (e.g. cancer, fractures, spinal stenosis, infections),
- Complicated back problems (e.g. prior back surgery, medicolegal issues),
- Possible contraindications for acupuncture (e.g. coagulation disorders, cardiac pacemakers, pregnancy, seizure disorder), and conditions that might confound acupuncture intervention effects or interpretation of results (e.g. severe fibromyalgia, rheumatoid arthritis).
- Conditions making acupuncture difficult (e.g. paralysis, psychoses),
- Prior acupuncture treatment for back pain; 1 year wait for any other type.
- The intent to undergo surgery during the time of involvement in the study.
- History of cardiac, respiratory, or nervous system disease that, in Dr. Wasan's judgment, precludes participation in the study because of a heightened potential for adverse outcome. For example: asthma or claustrophobia.
- Presence of any contraindications to MRI scanning. For example: cardiac pacemaker, metal implants, fear of closed spaces, pregnancy.
- Involvement in workmen's compensation or disability claims.
- Radicular pain extending below the knee.
- Active substance abuse disorders within the last 24 months, based on subject self-report.
- Use of more than 60 mg morphine equivalent prescription opioids or steroids for pain.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Traditional Acupuncture
Participants will receive acupuncture over 6 30-minute sessions.
|
|
Experimental: Laser Acupuncture
Participants will receive laser acupuncture over 6 30-minute sessions.
|
|
No Intervention: Wait-List
Subjects will be put on a 6 week wait-list and receive vouchers for acupuncture at a local clinic.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Pain improvement in patients with lower back pain
Time Frame: 6 weeks
|
Pain rating changes for chronic low back pain after acupuncture sessions.
|
6 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Robert R Edwards, Ph.D., Brigham and Women's Hospital
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 1, 2012
Primary Completion (Actual)
May 1, 2017
Study Completion (Actual)
October 1, 2017
Study Registration Dates
First Submitted
May 11, 2012
First Submitted That Met QC Criteria
May 14, 2012
First Posted (Estimate)
May 15, 2012
Study Record Updates
Last Update Posted (Actual)
November 29, 2017
Last Update Submitted That Met QC Criteria
November 27, 2017
Last Verified
November 1, 2017
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2011P001364
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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