Dose-response: Exercise Therapy on Hip Osteoarthritis

Dose-response: Exercise Therapy on Hip Osteoarthritis, a Pilot Study

Osteoarthritis is a common disease that causes muscle weakness, stiffness and instability. The disease reduces the opportunities for an active lifestyle. Exercise Therapy provides a well-documented effect on pain and function in patients with osteoarthritis of the hip. It is sought an optimal dose of exercise, in which this study will help to investigate.

We hypothesize that an exercise program designed to have a high number of repetitions will benefit the outcome of the training in a more positive way than a low-repetition based program.

Study Overview

• Status: Completed
• Conditions: Osteoarthritis, Hip
• Intervention / Treatment: Other: High-Dosage Exercise Therapy; Other: Low-Dosage Exercise Therapy

• Study Type: Interventional
• Enrollment (Actual): 35
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Norway
  • Ørsta, Norway, 6154
    • Fysioterapitjenesten i Ørsta

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 45 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• At least three month since debut of the disease
• Age above 45 years
• Ability to complete the intervention

Exclusion Criteria:

• Pain above 4 on VAS during gait
• Pregnancy
• Autoimmune disease
• Cardiovascular disease
• Respiratory disease
• Metabolic disease
• Neurological signs
• Planned hip-replacement surgery within the next year
• Received exercise therapy within the last 3 months

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: High-dosage-group	Other: High-Dosage Exercise Therapy; Structure of the exercise program done three times per week, for eight weeks: 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 30 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 30 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.)
Active Comparator: Low-dosage-group	Other: Low-Dosage Exercise Therapy; Structure of the exercise program done three times per week, for eight weeks: 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 10 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 10 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
WOMAC Index of Osteoarthritis (questionnaire)	WOMAC Index of Osteoarthritis (questionnaire)	0 weeks, 8 weeks, 6 months postinterventional

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
HAD questionnaire		0 weeks, 8 weeks, 6 months postinterventional
Tampa Scale for Kinesiophobia		0 weeks, 8 weeks, 6 months postinterventional
Squats	Number of squats completed in 30 seconds.	0 weeks, 8 weeks, 6 months postinterventional
Stairs	Time used to walk up and down 12 steps.	0 weeks, 8 weeks, 6 months postinterventional

Collaborators and Investigators

• Sponsor: Norwegian University of Science and Technology
• Investigators: Principal Investigator: Håvard Østerås, Norwegian University of Science and Technology

Publications and helpful links

General Publications

• Osteras H, Paulsberg F, Olsen SE, Osteras B, Torstensen TA. Effects of medical exercise therapy in patients with hip osteoarthritis: A randomized controlled trial with six months follow-up. A pilot study. J Bodyw Mov Ther. 2017 Apr;21(2):284-289. doi: 10.1016/j.jbmt.2016.06.016. Epub 2016 Jul 5.

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2012
• Primary Completion (Actual): December 1, 2014
• Study Completion (Actual): December 1, 2014

Study Registration Dates

• First Submitted: October 1, 2012
• First Submitted That Met QC Criteria: October 2, 2012
• First Posted (Estimate): October 4, 2012

Study Record Updates

• Last Update Posted (Actual): September 21, 2017
• Last Update Submitted That Met QC Criteria: September 19, 2017
• Last Verified: September 1, 2017

More Information

Terms related to this study

• Keywords: Exercise therapy
• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Hip
• Other Study ID Numbers: DROAPS1

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No