Quantification, Analysis and Simulation of Facial Mimics Movements (SIMOVI-IRM)

February 7, 2023 updated by: Centre Hospitalier Universitaire, Amiens

The SIMOVI project is a collaboration between our Department of Maxillofacial Surgery (CHU Amiens) and the Biomechanical bioengineer Research Department and Roberval Labs (Technological University of Compiègne). The question raised is the extent to which a facial mimic can be evaluated objectively. In today's clinical practice, the investigators use grading systems based on muscular scale or testing, in order to evaluate a facial muscular disorder. This assessment remains subjective because the investigators are deducing from surfacing cutaneous deformations the movement quality of the solicited muscle.

This qualitative approach is therefore an approximate approach and deserves to be better thought to plan a surgical treatment which involves mimic facial muscle (as rehabilitation of facial palsy, cleft palate for example), to monitor the results, and to follow the recovery and progress in physiotherapy care.

The aim of this study is to correlate external soft tissue movement (essentially cutaneous) during facial mimic with internal movement (essentially facial mimic muscle) using qualitative and QUANTITATIVE indicators, and to perform a biomechanical model of selected mimic face's movement using the precedent data.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
    • Picardie
      • Amiens, Picardie, France, 80054
        • Amiens university hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 30 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Caucasian subject
  • Ability to provide informed consent

Exclusion Criteria:

  • Facial pathology
  • Facial trauma
  • Pregnant or breastfeeding.
  • Contraindications to MRI

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: DIAGNOSTIC
  • Allocation: NA
  • Interventional Model: SINGLE_GROUP
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Mimic facial muscle from 3T MRI data
Other: Magnetic Resonance Imaging (MRI), Surface scan, Motion capture, Digital Image Correlation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Morphometric assessment of mimic facial muscle from 3T MRI data
Time Frame: 30 min
The aim is to valid a method to identify, describe and measure the mimic facial muscles in 3 Tesla MRI. Through particular MRI acquisition developed especially for mimic facial muscle from routine acquisition, Morphometrics properties are calculated as length, volume, thickness and cross physiological section area.
30 min

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Three dimensional quantitative analysis of mimics through motion capture
Time Frame: 01 hour

A VICON motion capture system with the Nexus 1.7.1 software will be used to capture expressive facial movements at a 120 Hz sample rate with 7 T160 cameras and 2 MX30 cameras. Markers of a diameter of 1.5 mm will be placed on the face. The localization of the markers is related to the muscles involved in the movements we want to study.

After data capture, we build and reconstruct our model. We chose a neutral pose as reference. The best parameters for the reconstruction will be determined. Kinematic parameters will be the markers displacement.
01 hour
Three dimensional quantitative mimic facial analysis with surface scan.
Time Frame: 01 hour
Three-dimensional image captured with a MH WHALE 3D Scanner.
01 hour
Three dimensional analysis with Digital Image Correlation
Time Frame: 01 hour

Recording three-dimensional images of the deformations of the face by two pairs of Pike CCD cameras from Allied Vision Technologies, with Schneider Xenoplan 2.0/28mm Lens, positioned on both sides of the face.

The calibration and the image processing will be made with the software suite VIC-SNAP, VIC-3D and 3D Fusion (Correlated Solutions)
01 hour

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Centre Hospitalier Universitaire, Amiens

Collaborators

Regional Council Picardie, France

Investigators

  • Study Director: Bernard DEVAUCHELLE, MD, phD, Department of Maxillofacial Surgery, Amiens University Hospital
  • Principal Investigator: Stéphanie DAKPE, MD, Department of Maxillofacial Surgery, Amiens University Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

August 8, 2011

Primary Completion (ACTUAL)

February 1, 2022

Study Completion (ACTUAL)

February 1, 2022

Study Registration Dates

First Submitted

December 2, 2013

First Submitted That Met QC Criteria

December 5, 2013

First Posted (ESTIMATE)

December 6, 2013

Study Record Updates

Last Update Posted (ESTIMATE)

February 9, 2023

Last Update Submitted That Met QC Criteria

February 7, 2023

Last Verified

February 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • PI11-DR-DAKPE
  • 2011-A00532-39 (OTHER: ID-RCB)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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