- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02244476
Acoustic Tribology Validation Study
October 13, 2017 updated by: NIZO Food Research
Validation Study to Evaluate the Use of Acoustic Tribology to Assess Mouthfeel of Dairy Drinks
Dairy-based beverages contain fat and sugars.
As both contribute to the energy intake upon consumption, food industry strives to reduce these ingredients while maintaining the taste, texture and aroma properties of the beverages.
A successful reduction of fat and sugar from drinks has still proven a great challenge since consumers have less preference for the mouth feel of reformulated beverages than for the regular beverages.
Mainly because instrumental measures like rheology and traditional tribology do not entirely predict the experienced mouth feel, there is an interest in alternative correlates for mouth feel aspects related to fat and sugar perception.
In a recent study it was demonstrated that vibrations produced during interaction between the tongue, palate and beverages during consumption are very sensitive to the amount of fat and texturizers in the beverage.
The present study aims at clarifying that relation for a larger panel of human subjects, by systematically evaluating vibration spectra during consumption of dairy beverages that differ in fat content, sugar content or pH.
Secondly, the correlation of vibration spectra (acoustic tribology) with mouth feel-related sensory properties and composition of fat deposits on the tongue will be assessed.
Study Overview
Status
Completed
Study Type
Observational
Enrollment (Actual)
17
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Ede, Netherlands, 6718 ZB
- NIZO food research
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
16 volunteers from the local general population
Description
Inclusion Criteria:
- Age 18-65 years
- Healthy set of teeth
- Ability to work with sensory descriptors for dairy products.
- Able to produce an acoustic signal that is larger than the background signal
- Voluntary participation
- Having given written informed consent
- Willing to comply with study procedures
- Willing to accept use of all encoded data, including publication, and the confidential use and storage of all data
- Willing to accept disclosure of the financial benefit of participation in the study to the authorities concerned
Exclusion Criteria:
- Wearing dentures
- Inability to comply with instructions for acoustic tribology
- A self-reported food allergy or sensitivity for ingredients of the test products
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Powers in segments of time-frequency transferred vibration data
Time Frame: between 2s and 20s after consumption of each sip
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Spectral powers of acoustic signals (in V^2/s) produced by tongue-palate interactions during consumption of various foods in the bands 60-300Hz and 400-2000Hz.
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between 2s and 20s after consumption of each sip
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Ratios of powers in segments of time-frequency transferred vibration data
Time Frame: 2-20 seconds after consumption of each sip
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Ratios of spectral powers in the 400-2000Hz band over powers in the 60-300Hz band of acoustic signals produced by tongue-palate interactions during consumption of various foods (unit-free).
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2-20 seconds after consumption of each sip
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Reported rating of product thickness
Time Frame: 0-2 sec after consumption of each sip
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Evaluation of product thickness on a Visual Analogue Scale (mm distance from the lower anchor)
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0-2 sec after consumption of each sip
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Relative fat content in the collected tongue coating
Time Frame: 2-20 sec after consumption of each sip
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percentage of fat encountered in tongue coating that was collected with a swab immediately after consumption
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2-20 sec after consumption of each sip
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Reported rating of product Creaminess
Time Frame: 0-2 sec after consumption of each sip
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Evaluation of product creaminess on a Visual Analogue Scale (mm distance from the lower anchor)
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0-2 sec after consumption of each sip
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Reported rating of product Roughness
Time Frame: 0-2 sec after consumption of each sip
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Evaluation of product roughness on a Visual Analogue Scale (mm distance from the lower anchor)
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0-2 sec after consumption of each sip
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Relative sugar content in the collected tongue coating
Time Frame: 2-20 seconds after bite consumption
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percentage of sugars encountered in tongue coating that was collected with a swab immediately after consumption
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2-20 seconds after bite consumption
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Relative protein content in the collected tongue coating
Time Frame: 2-20 seconds after bite consumption
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percentage of protein encountered in tongue coating that was collected with a swab immediately after consumption
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2-20 seconds after bite consumption
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Harold Bult, PhD, NIZO food research
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
November 1, 2014
Primary Completion (Actual)
January 1, 2015
Study Completion (Actual)
January 1, 2015
Study Registration Dates
First Submitted
September 8, 2014
First Submitted That Met QC Criteria
September 16, 2014
First Posted (Estimate)
September 19, 2014
Study Record Updates
Last Update Posted (Actual)
October 16, 2017
Last Update Submitted That Met QC Criteria
October 13, 2017
Last Verified
October 1, 2017
More Information
Terms related to this study
Other Study ID Numbers
- NIZO 105356
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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