Clostridium Difficile Infection: the First Report in Southeast Asia by 2010 Nationwide Study

The Burden of Clostridium Difficile Infection in Thai Population: the First Report in Southeast Asia by 2010 Nationwide Study

The authors retrieved in-patient medical data, including the expense, from the 2010 Thailand Nationwide Hospital Admission Database, which is part of the National Health Security Office (NHSO). The diagnosis of digestive diseases with any form of colitis listed in the causes, either as principal diagnosis or co-morbidity, coding by the ICD-10 was recorded. The inclusion criteria were: 1) diagnosis of enterocolitis due to Clostridium difficile (ICD10-A07); and 2) age of more than 18 years. If the data was incomplete, the case was excluded. The baseline characteristics, including age, sex, co-morbidity disease and history of endoscopy or surgery, were recorded. The burden of CDI was evaluated by length of hospital stay (LOS), mortality rate, and hospital charge.

Study Overview

• Status: Completed
• Conditions: Clostridium Difficile Infection
• Intervention / Treatment: Other: Colitis with CDI treatment

• Study Type: Observational
• Enrollment (Actual): 204666

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The patients with the diagnosis of Clostridium difficile (ICD10-A07) with age of more than 18 years were included.

Description

Inclusion Criteria:

• The patients with the diagnosis of Clostridium difficile (ICD10-A07)
• Age of more than 18 years.

Exclusion Criteria:

• Data incompleted

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Retrospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Colitis with CDI; Patients who diagnosed with CDI will be analysed	Other: Colitis with CDI treatment; All patients will be treated with standard treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Death rate and length of hospital stay in CDI during admission	Length of hospital stay(LOS), mortality rate and hospital charge were used as the indicators for evaluating the burden of CDI.	participants will be followed for the duration of hospital stay, an expected average of 2 weeks
Hospital charge of CDI	Length of hospital stay(LOS), mortality rate and hospital charge were used as the indicators for evaluating the burden of CDI.	participants will be followed for the duration of hospital stay, an expected average of 2 weeks

Collaborators and Investigators

• Sponsor: King Chulalongkorn Memorial Hospital
• Investigators: Principal Investigator: Rapat Pittayanon, MD, King Chulalongkorn Memorial Hospital

Study record dates

Study Major Dates

• Study Start: January 1, 2010
• Primary Completion (Actual): December 1, 2010
• Study Completion (Actual): December 1, 2014

Study Registration Dates

• First Submitted: December 22, 2014
• First Submitted That Met QC Criteria: December 24, 2014
• First Posted (Estimate): December 30, 2014

Study Record Updates

• Last Update Posted (Estimate): December 30, 2014
• Last Update Submitted That Met QC Criteria: December 24, 2014
• Last Verified: December 1, 2014

More Information

Terms related to this study

• Keywords: Epidemiology; Thailand; Clostridium difficile infection; burden; nationwide study; South East Asia; Outcome Assessment (Health Care) [N04.761.559.590]
• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Bacterial Infections; Bacterial Infections and Mycoses; Gram-Positive Bacterial Infections; Infections; Communicable Diseases; Clostridium Infections
• Other Study ID Numbers: RP009