- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02678078
Characterization of Cancer Tissue Using 3D Biosynthetic Material
May 5, 2016 updated by: Dror Seliktar, Technion, Israel Institute of Technology
Characterization of Cancer Tissue Using 3D Biosynthetic Materials.
Using liver biopsy from stage 4 cancer patients, the investigators will evaluate and characterize the metastatic cells.
Study Overview
Detailed Description
The investigators' biomaterial lab has developed an in vitro diagnostic system in which a cancer tumor is placed inside a 3D hydrogel.
This material has similar properties to the human tissue and can visualize cell migration and proliferation.
In this system, the investigators have already characterised human metastatic cells obtained from nude mice tumors.
The diagnostic assay is able to evaluate the reduction in cell growth associated with anti-cancer drug therapy.
The next step is to test the in vitro diagnostic system using human tissue samples from human patients, and to validate the system as a simple and effective a priori diagnostic tool for characterizing patient tumours.
Study Type
Observational
Enrollment (Anticipated)
100
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: tarek Saadi, Dr.
- Phone Number: 97247772947
- Email: t_saadi@rambam.health.gov.il
Study Contact Backup
- Name: shlomit harpaz, Msc
- Phone Number: 972544565257
- Email: shlomith@tx.technion.ac.il
Study Locations
-
-
-
Haifa, Israel
- Recruiting
- Rambam
-
Contact:
- Tarek Saadi, Dr.
- Phone Number: 972502064575
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (ADULT, OLDER_ADULT)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
every man or women 18 years old or older, with a liver tumor.
Description
Inclusion Criteria:
- liver tumor
Exclusion Criteria:
- refuse to volunteer
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
cell growth
Time Frame: 1 week
|
biopsy will be placed inside 3D gel, and growth will be measured over 1 week time.
|
1 week
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Study Director: Dror seliktar, Prof, Technion, Israel Institute of Technology
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 2016
Primary Completion (ANTICIPATED)
January 1, 2018
Study Completion (ANTICIPATED)
January 1, 2018
Study Registration Dates
First Submitted
February 4, 2016
First Submitted That Met QC Criteria
February 8, 2016
First Posted (ESTIMATE)
February 9, 2016
Study Record Updates
Last Update Posted (ESTIMATE)
May 6, 2016
Last Update Submitted That Met QC Criteria
May 5, 2016
Last Verified
May 1, 2016
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 0671-15-RMB
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Cancer
-
University of Michigan Rogel Cancer CenterRecruitingCancer Liver | Cancer Brain | Cancer Head &Neck | Cancer PelvisUnited States
-
Cellworks Group Inc.RecruitingCancer | Relapsed Cancer | Refractory CancerUnited States
-
Vanderbilt-Ingram Cancer CenterNational Institutes of Health (NIH)Active, not recruitingAdvanced Cancer | Relapsed Cancer | Refractory CancerUnited States
-
UNC Lineberger Comprehensive Cancer CenterHyundai Hope On WheelsRecruitingCancer | Pediatric Cancer | Survivorship | Cancer MetastaticUnited States
-
MiRXES Pte LtdRecruitingBreast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Thoracic Cancer | Liver CancerSingapore
-
Sidney Kimmel Cancer Center at Thomas Jefferson...CompletedStage I Breast Cancer | Stage I Uterine Corpus Cancer | Stage II Uterine Corpus Cancer | Stage III Uterine Corpus Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage... and other conditionsUnited States
-
Massachusetts General HospitalNational Comprehensive Cancer NetworkCompletedGastric Cancer | Pancreatic Cancer | Esophageal Cancer | Rectal Cancer | Colon Cancer | Hepatobiliary CancerUnited States
-
Johns Hopkins UniversityNational Cancer Institute (NCI); National Institute on Minority Health and...Enrolling by invitationCancer | Advanced Cancer | End Stage Cancer | MalignancyUnited States
-
City of Hope Medical CenterNational Cancer Institute (NCI)CompletedStage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IV Gastric Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic Cancer | Stage IVB Colorectal Cancer | Stage IVB Pancreatic Cancer | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric... and other conditionsUnited States
-
Case Comprehensive Cancer CenterCompletedStage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer and other conditionsUnited States
Clinical Trials on Analyzing biopsy samples
-
University Hospital, BordeauxRecruitingSystemic Sclerosis | SclerodermaFrance
-
University Hospital, Strasbourg, FranceCompletedSmall Cell Lung Cancer | Non-Small Cell Lung CarcinomaFrance
-
Assistance Publique Hopitaux De MarseilleSuspendedAortic Valve Regurgitation AcquiredFrance
-
University Hospital, BordeauxSociete Francaise de RhumatologieCompleted
-
Seda Yilmaz SemerciCompletedBronchopulmonary DisplasiaTurkey
-
Assistance Publique - Hôpitaux de ParisSociété de Dermatologie FrançaiseNot yet recruiting
-
Assistance Publique Hopitaux De MarseilleUnknown
-
Assistance Publique - Hôpitaux de ParisNot yet recruitingAutosomal Recessive Congenital Ichthyosis | Epidermolytic IchthyosisFrance
-
The Christie NHS Foundation TrustAstraZenecaCompletedNon-Small Cell Lung CancerUnited Kingdom
-
University Hospital, LilleRecruitingGraft Versus Host Disease | Extracorporeal PhotopheresisFrance