Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles

Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles:Prospective Observational Study

Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .

Study Overview

• Status: Unknown
• Conditions: Pregnancy

Detailed Description

The aim of this study is to assess the relationship between the position of the tip of the inner catheter, the position of the air bubbles (at time , 5 min ,10 min )after embryo transfer and pregnancy rate outcome in ICSI cycles. Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer, it is highly recommended to use agents that can facilitate a smooth embryo transfer and reduce unintended stimulation of the fundus, for example the application of soft-tipped catheters, which can improve pregnancy rate.

The advantage of using the air and liquid content for catheter loading is to prevent the embryo from adhering to the wall of the catheter at the time of injection.The presence of two air bubbles on both sides of the medium that contains the embryo prevents the transfer of the embryo within the catheter and beside, in the transfer under ultrasonographic guidance, the air bubbles are often considered a marker for the embryo's position in the uterus.

• Study Type: Observational
• Enrollment (Anticipated): 94

Contacts and Locations

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 40 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

• Sampling Method: Non-Probability Sample

Study Population

prospective observational study

Description

Inclusion Criteria:

• BMI < 30 kg/ m2.
• Between 20 and 35years old.
• FSH levels on cycle day 3 of <12 mIU/mL.
• Both ovaries present deprived of morphological abnormalities and adequately visualized in Transvaginal ultrasound.
• Grade one or two embryo quality.

Exclusion Criteria:

• Hydrosalpinx.
• Intrauterine lesion.
• Patients undergoing ET after cryopreservation.
• Blood present on the catheter during the transfer procedure.
• A difficult transfer or with a suspicion of touching the fundus.
• Endometrial thickness less than 8mm.
• Known allergic reaction against one of the ingredient of the medications used during the study.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
clinical pregnancy rate	one and half year

Collaborators and Investigators

• Sponsor: Ain Shams Maternity Hospital

Study record dates

Study Major Dates

• Study Start: October 1, 2016
• Primary Completion (Anticipated): January 1, 2017
• Study Completion (Anticipated): January 1, 2017

Study Registration Dates

• First Submitted: October 21, 2016
• First Submitted That Met QC Criteria: October 21, 2016
• First Posted (Estimate): October 24, 2016

Study Record Updates

• Last Update Posted (Estimate): October 24, 2016
• Last Update Submitted That Met QC Criteria: October 21, 2016
• Last Verified: October 1, 2016

More Information

Terms related to this study

• Keywords: clinical pregnancy rate after embryo transfer
• Other Study ID Numbers: MOHEgypt

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES