Acute Abdomen in Adults- a Prospective Study on Emergency Department Admissions

Acute Abdomen in Adults- a Prospective Study on Causes of Abdominal Pain Leading to Emergency Department Admission in Tampere University Hospital

This is a non-randomized, prospective, population-based, single-center study designed to evaluate conditions resulting emergency admission in patients with abdominal pain. Furthermore, we are interested in how many patients are discharged with "non-specific abdominal pain" but later readmitted and diagnosed with a specific diagnosis.

Study Overview

• Status: Recruiting
• Conditions: Abdominal Pain

Detailed Description

1000 adult patients with acute abdominal pain will be recruited at Tampere University Hospital Emergency department. The patients will fill in a questionaire about the symptoms and their duration. A urine sample will be collected for polyamine molecule analysis with an electronic nose. At later stage of the study, a serum sample for coeliac tests will be collected. Patient outcome will be obtained during the hospital stay, at one-month after discharge and at one year.

• Study Type: Observational
• Enrollment (Anticipated): 1000

Contacts and Locations

• Study Contact: Name: Mika T Ukkonen, MD, PhD, MEcon; Phone Number: +358443454523; Email: mika.ukkonen@fimnet.fi
• Study Contact Backup: Name: Leena M Saaristo, MD; Phone Number: +358405030201; Email: leena.saaristo@fimnet.fi

Study Locations

• Finland
  • Tampere, Finland
    • Recruiting
    • Tampere University Hospital
    • Contact: Satu-Liisa K Pauniaho, MD, PhD; Phone Number: +358505386783; Email: satu-liisa.pauniaho@pshp.fi
    • Contact: Mika T Ukkonen, MD, PhD, MEcon; Phone Number: +358443454523; Email: mika.ukkonen@fimnet.fi

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

the adult patients with abdominal pain admitted to the emergency department are included. One thousand patients from Tampere district will be chosen for analysis.

Description

Inclusion Criteria:

All adult patients with abdominal pain.

Exclusion Criteria:

Under the age of 18 years

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients with specific diagnose	Population based analysis of incidence of diseases	One month

Secondary Outcome Measures

Outcome Measure	Time Frame
Number of patients misdiagnosed in emergency department and requiring readmission	One month
Number of participants with treatment related adverse events	One month
Diagnostic accuracy of polyamine molecule analysis	One month
Number of patients with undiagnosed coeliac disease	One month

Collaborators and Investigators

• Sponsor: Tampere University Hospital
• Investigators: Principal Investigator: Satu-Liisa K Pauniaho, MD, PhD, Tampere University Hospital, Finland

Study record dates

Study Major Dates

• Study Start: June 1, 2016
• Primary Completion (Anticipated): December 1, 2021
• Study Completion (Anticipated): December 31, 2025

Study Registration Dates

• First Submitted: October 20, 2016
• First Submitted That Met QC Criteria: March 3, 2017
• First Posted (Actual): March 8, 2017

Study Record Updates

• Last Update Posted (Actual): March 6, 2020
• Last Update Submitted That Met QC Criteria: March 5, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Keywords: adult; emergency department; abdominal pain; celiac disease; electronic nose
• Additional Relevant MeSH Terms: Pathologic Processes; Pain; Neurologic Manifestations; Disease Attributes; Signs and Symptoms, Digestive; Emergencies; Abdominal Pain; Abdomen, Acute
• Other Study ID Numbers: R16006