- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03890159
Effects of Computer Assisted Cognitive Rehabilitation on Patients With Stroke
Effects of Computer Assisted Cognitive Rehabilitation on Patients With Stroke in Attention, Functional Independence and Quality of Life
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Hale Karapolat, M.D.
- Phone Number: +902323903682
- Email: halekarapolat@gmail.com
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Patients over 18 years of age with stroke
Exclusion Criteria:
- Problems with sight
- Comorbid neurological disease
- Cognitive impairment prior to stroke
- Neglect Syndrome
- Wernicke or Global aphasia
Study Plan
How is the study designed?
Design Details
- Primary Purpose: SUPPORTIVE_CARE
- Allocation: RANDOMIZED
- Interventional Model: PARALLEL
- Masking: DOUBLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: Computer Assisted Cognitive Rehabilitation
Patients will receive their therapies 1 day a day, 2-3 days a week.
The computer-aided cognitive rehabilitation group will perform simulation-based exercises, including exercises related to attention, in a special computer program (Cogniplus TR version) during therapy hours, and patients will progress to the difficulty level automatically.
Their performance during this process (response time etc.) will be recorded.
|
Patients will receive their therapies 1 day a day, 2-3 days a week.
The computer-aided cognitive rehabilitation group will perform simulation-based exercises, including exercises related to attention, in a special computer program (Cogniplus TR version) during therapy hours.
The total duration of intervention will be 1 month.
|
EXPERIMENTAL: Conventional Cognitive Rehabilitation
The home (paper pen) exercise group will take the necessary exercises on paper suitable for their respective levels and the daily tasks suitable for their functional needs and interests.
|
Patients will receive their therapies 1 day a day, 2-3 days a week.
The home (paper pen) exercise group will take the necessary exercises on paper suitable for their respective levels and the daily tasks suitable for their functional needs and interests.
The total duration of intervention will be 1 month.
|
NO_INTERVENTION: Waiting list controls
These patients will get no intervention as means of cognitive rehabilitation, but will get their usual treatments.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Stroop test
Time Frame: 1 month
|
Stroop test is a quick measurement for ability of color perception and focusing attention Participants are asked to read 112 words with color within 2 min.
Then, they are required to tell the color of these 112 words as color-word association.
Finally, time of accomplishing task and number of correct read, corrections and errors are examined.
|
1 month
|
Trail making
Time Frame: 1 month
|
Trail making test is used to evaluate the attention and velocity.
Participants are asked to sequentially connect 25 circles with number which was written in only one style (Line A), or to sequentially connect 25 circles with number which was written in two styles (Line B).
The time used to complete the line A or B and the number of errors and fouls are recorded and analyzed.
|
1 month
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Beck Depression Index
Time Frame: Baseline, Month 1
|
It is a test frequently used to assess depressive symptoms in chronic diseases.
It is comprised of 21 items, 8 of which investigate the somatic symptoms of depression (such as loss of appetite and difficulty sleeping) and 13 of which address the cognitive-affective symptoms of depression (e.g., despair, social withdrawal).
The BDI is scored as follows: 0-9: no symptoms; 10-16: mild depression; 17-29: moderate depression; and 30-63: severe depression
|
Baseline, Month 1
|
Quality of Life Assessment
Time Frame: 1 month
|
Medical Outcomes Study 36-item Short Form Survey (SF-36).
This is one of the most widely used scales evaluating quality of life.
The SF-36 explores eight dimensions of the quality of life "physical function", "physical role", "bodily pain", "general health", "vitality", "social function", "emotional role" and "mental health".
All scales were linearly transformed to a 0 to 100 scoring, with 100 indicating most favorable health state and 0 indicating the least favorable health state
|
1 month
|
Functional Independence
Time Frame: 1 month
|
The FIM is a generic and global activity scale that measures an individual's independence in conducting his or her daily fundamental physical and cognitive activities. The FIM measures 81 items in two areas: 1) physical/motor function (13 items) and 2) cognitive/ psychosocial function (5 items). The items are divided into six subgroups according to activities, four physical and two cognitive. Each item is scored on a scale of one to seven, with "level 1" indicating that the patient needs complete help and "level 7" indicating complete independence. The total FIM score varies between 18 and 126. |
1 month
|
Collaborators and Investigators
Sponsor
Publications and helpful links
Study record dates
Study Major Dates
Study Start (ANTICIPATED)
Primary Completion (ANTICIPATED)
Study Completion (ANTICIPATED)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ACTUAL)
Study Record Updates
Last Update Posted (ACTUAL)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Stroke-CACR
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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