The Movement Imagery Ability in Patients With Familial Mediterranean Fever

Motor imagery is the mental representation of movement without any doing body movement. A main function of imagery is to aid the self-regulation of thoughts, feelings, and behaviours. Studies have shown to be more effective for individuals displaying a higher level of imagery ability when using imagery to improve motor and motivational outcomes, including self-efficacy. The aim of this study is to measure the movement imagery ability in patients with Familial Mediterranean Fever and compare it with healthy individuals.

Study Overview

• Status: Completed
• Conditions: Familial Mediterranean Fever
• Intervention / Treatment: Behavioral: movement imagery ability

Detailed Description

Familial Mediterranean Fever (FMF) is an autosomal recessive disease characterized by recurrent and self-limited attacks of fever associated with abdominal, chest, and joint pain. Previous studies have shown that individuals with FMF are more limited in terms of physical function than the normal population, and depression and anxiety are more common in these individuals. Being a lifetime disease, quality of life, and mental health can be affected due to serious complications such as attack frequency, disease resistance, and sometimes amyloidosis. Mental imagery is the ability to imaging the movement without doing the physical execution of the movement. During the last years, mental imagery is used in clinical practice as a tool for the treatment of chronic pain. Pain differs in patients with rheumatic diseases. Stress is one of the predictors of pain in patients with FMF. Even if the frequency is variable when attacks happen they may affect patients physically and their mental health and the ability to cope. A main function of imagery is to aid the self-regulation of thoughts, feelings, and behaviors. To use imagery for motor and motivational outcomes firstly the imagery ability levels should be measured.

• Study Type: Observational
• Enrollment (Actual): 60

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey
    • Istanbul University, Cerrahpaşa Medical Faculty, Department of Rheumatology

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients with Familial Mediterranean Fever and Healthy Controls

Description

Inclusion Criteria:

• having had at least one attack last year
• co-operated individuals

Exclusion Criteria:

• patients with a neurological disorder,
• diagnosed with cancer,
• cognitive impairment,
• having a primary pathology of the musculoskeletal system,
• having previous imagery practice,
• having an additional rheumatic disease

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Familial Mediterranean Fever group; 30 participants	Behavioral: movement imagery ability; Determining the movement imagery ability: internal visual, external visual and kinesthetic imagery
Healthy group; 30 participants	Behavioral: movement imagery ability; Determining the movement imagery ability: internal visual, external visual and kinesthetic imagery

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Movement Imagery Questionnaire-3 (MIQ-3)	It is a questionnaire containing 12 items to evaluate the visual imagination skills of the individual. It evaluates internal visual imagery, external visual imagery, and kinesthetic imagery. For each item, first of all, individuals read the description of the movement, and then it is desired to perform the movement physically and after that, the same movement is requested. Individuals evaluate the degree of imagination on a 7-point Likert-type scale ranging from 1 (very difficult to see/feel) to 7 (very easy to see/feel). The motion visualization questionnaire has good psychometric properties, internal reliability, and estimated validity.	Baseline

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
McGill Melzack Pain Questionnaire (MPQ)	MPQ consists of 78 descriptors grouped into four categories: sensory, affective, evaluative, and miscellaneous. These four categories were grouped into 20 subclasses each made up of 2 to 6 words according to pain intensity. Patients were asked to choose the pain descriptors according to the type of pain they felt during the attack episodes. Patients were instructed to choose one of the words that best described their type of pain experience. Changing of pain with time was assessed. Pain right now, pain at its worst and pain at its least was evaluated. Pain exacerbating or relieving factors were recorded.	Baseline
Pain Catastrophizing Scale	Pain Catastrophizing Scale identifies catastrophic thoughts or feelings and ineffective coping strategies of patients. PCS is a Likert-type self-assessment scale consisting of thirteen items. Each item is evaluated between 0 and 4 points. The total score ranges from 0 to 52. Includes rumination, magnification, and helplessness subscales. High scores indicate that the level of disaster is high.	Baseline

Collaborators and Investigators

• Sponsor: Medipol University
• Collaborators: Istanbul University - Cerrahpasa (IUC)
• Investigators: Principal Investigator: Albina Alikaj, MSc, Medipol University; Study Chair: Ahsen Büyükaslan, MSc, Medipol University; Study Director: Serdal Uğurlu, Prof, Istanbul University - Cerrahpasa (IUC); Study Director: Burcu Dilek, PhD, Acibadem University

Publications and helpful links

Helpful Links

• Reliability and validity of the Turkish version of the movement imagery questionnaire-3: Its cultural adaptation and psychometric properties
• Kuǧuoǧlu S, Aslan FE, Olgun N. Turkish version of the McGill Melzack Pain Questionnaire Form (MPQF). Vol. 15, Agri. 2003. 47-51 p.

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2018
• Primary Completion (Actual): February 13, 2021
• Study Completion (Actual): February 18, 2021

Study Registration Dates

• First Submitted: January 24, 2021
• First Submitted That Met QC Criteria: January 24, 2021
• First Posted (Actual): January 28, 2021

Study Record Updates

• Last Update Posted (Actual): August 2, 2022
• Last Update Submitted That Met QC Criteria: August 1, 2022
• Last Verified: August 1, 2022

More Information

Terms related to this study

• Keywords: pain; catastrophizing; movement imagery ability; familial mediterranean fever
• Additional Relevant MeSH Terms: Skin Diseases; Infections; Genetic Diseases, Inborn; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Skin Diseases, Genetic; Body Temperature Changes; Fever; Brucellosis; Familial Mediterranean Fever; Hereditary Autoinflammatory Diseases
• Other Study ID Numbers: 10840098-604.01.01-E.399988

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No